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TM4SF5 Knockout Cell Lines

Gene: TM4SF5

Official Full Name: transmembrane 4 L six family member 5provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence and structure to transmembrane 4 superfamily member 1. It may play a role in cell proliferation, and overexpression of this protein may be associated with the uncontrolled growth of tumour cells. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33636 TM4SF5 Knockout cell line (A549) Human TM4SF5 1:3~1:4 Negative Online Inquiry

Background

TM4SF5 Gene Knockout Cell Lines are meticulously engineered cellular models designed to elucidate the specific functions of the TM4SF5 gene, which is known to play a crucial role in various physiological processes, including cell adhesion, migration, and proliferation. By utilizing CRISPR-Cas9 technology, these cell lines provide a powerful platform for researchers to investigate the molecular pathways regulated by TM4SF5, thereby advancing our understanding of its contributions to both normal physiological functions and pathological conditions.

The primary function of these knockout cell lines is to enable the study of the consequences of the absence of the TM4SF5 gene. By observing the cellular behavior in environments where TM4SF5 is non-functional, researchers can identify significant alterations in cellular signaling pathways, elucidate how cells respond to environmental cues, and determine the gene's role in disease mechanisms including cancer metastasis and other disorders. This functionality is essential for translating basic scientific findings into potential therapeutic strategies.

Scientifically, TM4SF5 has emerged as a key player in the research into cell biology and oncology, making the development of knockout models vital for both academic and clinical research applications. These cell lines serve as invaluable tools for drug screening, enabling the evaluation of therapeutic compounds targeting TM4SF5-related pathways and offering insights into their mechanisms of action.

When compared to other gene knockout models, TM4SF5 Gene Knockout Cell Lines stand out due to their precise genetic modifications and the thorough validation protocols followed in their development. Researchers benefit from the inherent specificity and reliability of these models, providing greater confidence in experimental results. Additionally, our team is committed to ensuring that these cell lines are accessible and affordable, enabling a wider array of researchers and clinicians to leverage these tools in their work.

Our company's extensive experience in genetic engineering and cell line development, combined with a dedication to advancing research in the life sciences, underscores our commitment to delivering high-quality biological products. By choosing TM4SF5 Gene Knockout Cell Lines, you are equipping your laboratory with a cutting-edge resource that will propel your research and therapeutic endeavors forward, driving discoveries in gene function and disease understanding.

Please note that all services are for research use only. Not intended for any clinical use.

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