Gene: TIMMDC1
Official Full Name: translocase of inner mitochondrial membrane domain containing 1provided by HGNC
Gene Summary: Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion and nucleoplasm. Implicated in nuclear type mitochondrial complex I deficiency 31. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22714 | TIMMDC1 Knockout cell line (HeLa) | Human | TIMMDC1 | 1:3~1:6 | Negative | Online Inquiry |
KO22715 | TIMMDC1 Knockout cell line (HCT 116) | Human | TIMMDC1 | 1:2~1:4 | Negative | Online Inquiry |
KO22716 | TIMMDC1 Knockout cell line (HEK293) | Human | TIMMDC1 | 1:3~1:6 | Negative | Online Inquiry |
KO22717 | TIMMDC1 Knockout cell line (A549) | Human | TIMMDC1 | 1:3~1:4 | Negative | Online Inquiry |
TIMMDC1 Gene Knockout Cell Lines are specially engineered cellular models that have undergone genetic modification to disrupt the TIMMDC1 gene. This gene encodes a mitochondrial protein implicated in various essential cellular processes, including mitochondrial ribosome assembly and mitochondrial translation regulation. By creating knockout cell lines, researchers are equipped with powerful tools to study the functional implications of TIMMDC1 deficiency and its role in mitochondrial biology and associated pathologies.
The primary function of these knockout cell lines lies in their ability to facilitate investigations into the impact of disrupted mitochondrial function on cellular health. By eliminating the TIMMDC1 protein, these cell lines allow for the examination of downstream effects on cellular metabolism, oxidative stress responses, and the overall integrity of mitochondrial functions. Researchers can simulate and analyze disease states related to mitochondrial dysfunction, enhancing our understanding of conditions such as neurodegenerative disorders, metabolic syndromes, and aging.
In scientific applications, TIMMDC1 gene knockout cell lines provide critical insights into mitochondrial biology, serving as valuable models for drug discovery, genetic studies, and the elucidation of pathophysiological mechanisms. Compared to traditional cell lines, these genetically modified models offer an unprecedented level of specificity and relevance, enabling more accurate simulations of human disease processes.
The unique selling points of TIMMDC1 knockout cell lines include their customizable nature, which allows for the generation of specific variants tailored to particular research needs, and the robustness of the knockout which facilitates reproducibility in experimental outcomes. Moreover, the availability of validated characterization data and comprehensive protocols ensures that researchers can confidently utilize these models with minimal additional validation.
For researchers and clinicians seeking to unravel the complexities of mitochondrial dysfunction and its implications in human health, TIMMDC1 Gene Knockout Cell Lines are invaluable resources. They provide unparalleled opportunities to enhance understanding and develop targeted therapeutic strategies.
Our company specializes in producing precise and validated biological models for biomedical research. With a commitment to quality and innovation, we empower scientists around the globe to make groundbreaking discoveries in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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