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THUMPD2 Knockout Cell Lines

Gene: THUMPD2

Official Full Name: THUMP domain 2 tRNA and snRNA guanosine methyltransferaseprovided by HGNC

Gene Summary: Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25935 THUMPD2 Knockout cell line (HeLa) Human THUMPD2 1:3~1:6 Negative Online Inquiry
KO25936 THUMPD2 Knockout cell line (HCT 116) Human THUMPD2 1:2~1:4 Negative Online Inquiry
KO25937 THUMPD2 Knockout cell line (HEK293) Human THUMPD2 1:3~1:6 Negative Online Inquiry
KO25938 THUMPD2 Knockout cell line (A549) Human THUMPD2 1:3~1:4 Negative Online Inquiry

Background

THUMPD2 Gene Knockout Cell Lines are specialized cell models developed for investigating the biological function of the THUMPD2 gene, which encodes a protein implicated in various cellular processes, including ribosome biogenesis and RNA metabolism. By employing CRISPR-Cas9 technology, these cell lines are engineered to specifically disrupt the THUMPD2 gene, enabling researchers to study the downstream effects of its absence on cellular behavior and function.

The key function of the THUMPD2 Gene Knockout Cell Lines lies in their ability to facilitate research into the molecular pathways influenced by THUMPD2, thereby helping to elucidate its role in cellular processes such as proliferation, differentiation, and response to stress. By creating a controlled environment where the effects of the gene's knockout can be observed, researchers can analyze alterations in gene expression, protein interactions, and cellular phenotypes that arise from the loss of THUMPD2 function.

These cell lines hold significant scientific importance across both research and clinical settings. They provide a valuable tool for understanding the molecular underpinnings of diseases associated with THUMPD2, including cancer and developmental disorders. Investigators can leverage these cell lines to screen for therapeutic compounds or investigate potential genetic interventions that target pathways disrupted by the loss of THUMPD2.

Compared to alternative methods of gene knockout, the THUMPD2 Gene Knockout Cell Lines offer several advantages, including high specificity and efficiency due to the CRISPR/Cas9 methodology. Moreover, these cell lines are readily available and can be easily integrated into existing workflows, thus making them a practical choice for laboratories.

Research and clinical professionals looking to deepen their understanding of gene function or disease mechanisms will find THUMPD2 Gene Knockout Cell Lines to be an indispensable resource. By utilizing these models, they will be equipped to uncover new therapeutic strategies and gain insights that may lead to improved patient outcomes.

Your company’s commitment to advancing research is reflected in the quality and accessibility of our biological products. We specialize in delivering cutting-edge tools that empower researchers to push the boundaries of scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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