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THRAP3 Knockout Cell Lines

Gene: THRAP3

Official Full Name: thyroid hormone receptor associated protein 3provided by HGNC

Gene Summary: Enables nuclear thyroid hormone receptor binding activity; phosphoprotein binding activity; and transcription coactivator activity. Involved in positive regulation of circadian rhythm and regulation of gene expression. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in exon-exon junction complex and nuclear speck. Part of mediator complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32446 THRAP3 Knockout cell line (HeLa) Human THRAP3 1:3~1:6 Negative Online Inquiry
KO32447 THRAP3 Knockout cell line (HCT 116) Human THRAP3 1:2~1:4 Negative Online Inquiry
KO32448 THRAP3 Knockout cell line (HEK293) Human THRAP3 1:3~1:6 Negative Online Inquiry
KO32449 THRAP3 Knockout cell line (A549) Human THRAP3 1:3~1:4 Negative Online Inquiry

Background

THRAP3 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to inhibit the expression of the THRAP3 gene, a crucial player in RNA processing and gene regulation. Utilizing CRISPR/Cas9 technology, these cell lines enable researchers to explore the functional consequences of THRAP3 gene disruption with high specificity and efficiency. By effectively knocking out THRAP3, the resulting cell lines allow for detailed investigations into the gene's role in various biological processes, including transcription, mRNA splicing, and cellular response to stress.

The key functionality of THRAP3 Gene Knockout Cell Lines lies in their ability to serve as robust models for studying the implications of THRAP3 loss in cellular physiology. This manipulation can illuminate pathways disrupted in diseases such as cancer or other disorders involving abnormal gene expression. The high fidelity of CRISPR-based genome editing ensures that researchers can rely on these cell lines for reproducible results, opening avenues for understanding the molecular mechanisms underpinning THRAP3-associated conditions.

In the realm of scientific research and clinical applications, these knockout lines stand out for their potential in drug discovery and therapeutic development. By providing clear insights into how THRAP3 influences target pathways, investigators can accelerate the identification of novel therapeutic targets and improve the precision of treatment strategies. Compared to other gene knockout models, THRAP3 Gene Knockout Cell Lines offer a streamlined approach that reduces time and resource investment while delivering enhanced data quality.

For researchers, clinicians, and biotechnologists, the value of THRAP3 Gene Knockout Cell Lines lies in their capacity to enrich understanding and drive innovation in gene regulation studies. With extensive validation and characterization, these cell lines are invaluable tools for dissecting the functional roles of THRAP3 in a variety of biological contexts.

Our company prides itself on its deep expertise in genetic engineering and the development of cutting-edge biological products, ensuring that researchers have access to top-tier tools for advancing scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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