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THEMIS2 Knockout Cell Lines

Gene: THEMIS2

Official Full Name: thymocyte selection associated family member 2provided by HGNC

Gene Summary: Predicted to be involved in T cell receptor signaling pathway and regulation of B cell activation. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33214 THEMIS2 Knockout cell line (HCT 116) Human THEMIS2 1:2~1:4 Negative Online Inquiry
KO33215 THEMIS2 Knockout cell line (HEK293) Human THEMIS2 1:3~1:6 Negative Online Inquiry

Background

THEMIS2 Gene Knockout Cell Lines represent a revolutionary advancement in the field of molecular biology, specifically engineered to facilitate the study of the THEMIS2 gene's functional role in cellular mechanisms. These cell lines have been meticulously designed with CRISPR/Cas9 technology to create precise deletions within the THEMIS2 gene, thereby allowing researchers to investigate its involvement in various biological processes, including immune responses and cellular signaling pathways.

The core function of THEMIS2 Gene Knockout Cell Lines lies in their ability to provide a clear model for studying the effects of the absence of the THEMIS2 protein. This is critical for understanding its role in T-cell development and function, potentially leading to breakthroughs in the treatment of autoimmune diseases and cancer. The knockout mechanisms permit researchers to analyze phenotypic changes and gene expression alterations, facilitating deeper insights into the cellular repercussions of manipulating themis pathways.

Scientifically, these knockout cell lines hold immense value in both research and clinical settings. They enable the exploration of gene function in a controlled environment, providing a platform for drug discovery and validation of therapeutic targets. Furthermore, these cell lines can be invaluable for pharmacogenomic studies, where understanding genetic variations can inform treatment strategies tailored to patient-specific profiles.

Compared to traditional gene manipulation techniques, the THEMIS2 Gene Knockout Cell Lines offer superior precision, versatility, and reproducibility. Researchers benefit from expedited timelines in experimental setups and consistent results, ensuring that findings are both reliable and easy to interpret. Additionally, the application of CRISPR technology minimizes off-target effects, enhancing the integrity of experimental data.

For researchers and clinicians alike, the THEMIS2 Gene Knockout Cell Lines represent a pivotal tool in unraveling complex biological questions and advancing therapeutic interventions. With our company’s unwavering commitment to quality and cutting-edge innovation in biological research tools, we proudly offer these cell lines as a cornerstone in enhancing scientific inquiry and clinical applications related to immune system functioning and disease pathology.

Please note that all services are for research use only. Not intended for any clinical use.

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