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TFG Knockout Cell Lines

Gene: TFG

Official Full Name: trafficking from ER to golgi regulatorprovided by HGNC

Gene Summary: There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09804 TFG Knockout cell line (HeLa) Human TFG 1:3~1:6 Negative Online Inquiry
KO09805 TFG Knockout cell line (HCT 116) Human TFG 1:2~1:4 Negative Online Inquiry
KO09806 TFG Knockout cell line (HEK293) Human TFG 1:3~1:6 Negative Online Inquiry
KO09807 TFG Knockout cell line (A549) Human TFG 1:3~1:4 Negative Online Inquiry

Background

TFG Gene Knockout Cell Lines are genetically engineered cell lines in which the TFG (Tumor Protein p53-Inducible Nuclear Protein 1) gene has been inactivated. This process utilizes CRISPR/Cas9 technology or similar gene-editing techniques to create precise deletions or modifications within the genomic sequence of the TFG gene, allowing researchers to investigate its biological function and contribution to various cellular processes. These knockout cell lines represent an essential tool for studying gene function, pathways involved in oncogenesis, and cellular responses to stress.

The primary mechanism behind the utility of TFG Gene Knockout Cell Lines lies in their ability to provide insights into the roles of the TFG gene in cellular proliferation, differentiation, and apoptosis. By comparing the knockout lines to their wild-type counterparts, researchers can elucidate the impact of TFG gene disruption on cellular behavior and signaling, potentially revealing novel targets for therapeutic interventions in cancer and other diseases where TFG may play a critical role.

In both research and clinical settings, these knockout cell lines offer tremendous scientific value. They can be used to generate models of human diseases, screen for drug responses, or investigate molecular interactions that are critical for understanding pathophysiological conditions. Furthermore, the use of TFG Gene Knockout Cell Lines in high-throughput screening enables the identification of compounds or genetic modifiers that can restore normal function or mitigate disease phenotypes.

One of the most significant advantages of TFG Gene Knockout Cell Lines compared to traditional knockdown methods is the permanence of the gene inactivation. This allows for stable and consistent experimental conditions, leading to more reproducible results over extended periods. Additionally, our product is rigorously validated for specificity and efficiency, which sets it apart from competing products that may not have undergone the same level of testing.

For researchers and clinicians, the value of TFG Gene Knockout Cell Lines lies in their ability to provide critical insights that can aid in the development of transformative treatments. Our commitment to high-quality biological products, backed by extensive expertise in molecular biology and genetics, positions us as a trusted partner in advancing the field of biomedical research and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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