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TFDP2 Knockout Cell Lines

Gene: TFDP2

Official Full Name: transcription factor Dp-2provided by HGNC

Gene Summary: The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35032 TFDP2 Knockout cell line (HeLa) Human TFDP2 1:3~1:6 Negative Online Inquiry
KO35033 TFDP2 Knockout cell line (HCT 116) Human TFDP2 1:2~1:4 Negative Online Inquiry
KO35034 TFDP2 Knockout cell line (HEK293) Human TFDP2 1:3~1:6 Negative Online Inquiry
KO35035 TFDP2 Knockout cell line (A549) Human TFDP2 1:3~1:4 Negative Online Inquiry

Background

TFDP2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the transcription factor Dp-2 (TFDP2). This gene plays a pivotal role in regulating cellular processes such as the cell cycle, apoptosis, and transcription by partnering with various E2F transcription factors. By creating knockout cell lines where TFDP2 is nonfunctional, researchers can directly investigate the biological implications of its absence and assess the downstream effects on cellular signaling pathways and gene expression patterns.

The primary mechanism by which TFDP2 influences cellular function involves its interaction with E2F proteins, affecting the expression of genes critical for cell division and differentiation. In research and clinical applications, these knockout cell lines are invaluable for elucidating the role of TFDP2 in cancer biology, where its dysregulation has been implicated in tumorigenesis. By employing these cell lines, scientists can model specific genetic alterations, study resistance to therapeutics, or assess new drug candidates with a focus on targeting the molecular pathways involving E2F and its cofactors.

One significant advantage of the TFDP2 Gene Knockout Cell Lines is their precision and specificity, enabling researchers to generate unambiguous data regarding the role of TFDP2 in various biological contexts. Compared to traditional cell lines where multiple genetic factors may confound results, these knockout models provide a clearer understanding of cellular responses and drug interactions closely associated with TFDP2 functionality.

In addition to their scientific applications, these knockout cell lines serve as powerful tools for industry professionals engaged in developing targeted therapies for cancers with TFDP2 involvement. Their ease of use and reliability allow for consistent results, fostering confidence among researchers and clinicians.

With a commitment to advancing innovative research tools, our company specializes in providing high-quality biological products, including the TFDP2 Gene Knockout Cell Lines. Our expertise in cell line development and molecular biology ensures that our products meet the rigorous demands of modern scientific inquiry, empowering researchers to push the boundaries of discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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