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TEX264 Knockout Cell Lines

Gene: TEX264

Official Full Name: testis expressed 264, ER-phagy receptorprovided by HGNC

Gene Summary: Enables signaling receptor activity. Involved in protein-DNA covalent cross-linking repair. Acts upstream of or within reticulophagy. Located in several cellular components, including autophagosome membrane; endoplasmic reticulum membrane; and replication fork. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22606 TEX264 Knockout cell line (HeLa) Human TEX264 1:3~1:6 Negative Online Inquiry
KO22607 TEX264 Knockout cell line (HCT 116) Human TEX264 1:2~1:4 Negative Online Inquiry
KO22608 TEX264 Knockout cell line (HEK293) Human TEX264 1:3~1:6 Negative Online Inquiry
KO22609 TEX264 Knockout cell line (A549) Human TEX264 1:3~1:4 Negative Online Inquiry

Background

TEX264 Gene Knockout Cell Lines are cutting-edge, genetically engineered models designed to facilitate the investigation of TEX264 gene function in various biological processes. These cell lines have been rigorously created through the targeted deletion of the TEX264 gene, enabling researchers to study its role in cellular pathways and disease mechanisms without the confounding effects of native gene expression.

The fundamental mechanism of these knockout cell lines relies on advanced genome editing technologies, such as CRISPR-Cas9. By introducing specific guide RNAs alongside the Cas9 nuclease, the functionality of the TEX264 gene can be precisely disrupted, leading to a loss of protein expression. This disruption allows researchers to probe the gene's involvement in key cellular processes such as apoptosis, autophagy, and cell cycle regulation, thereby providing insights into disease states like cancer and neurodegenerative disorders where TEX264 may play a crucial role.

The scientific importance of TEX264 Gene Knockout Cell Lines is underscored by their applications in both research and clinical settings. They serve as invaluable tools for drug discovery, targeted therapy testing, and elucidating gene function, ultimately driving forward our understanding of complex biological systems. Compared to traditional cell line models that retain wild-type gene functionality, these knockout lines offer a more precise approach to isolate and examine the effects attributed to TEX264, making them indispensable in modern biomedical research.

What sets TEX264 Gene Knockout Cell Lines apart from alternative products is their high reproducibility and the collaborative expertise underpinning their design and validation. This product provides researchers with a reliable and consistent platform, ensuring that experimental outcomes can be confidently interpreted and utilized for advancing scientific knowledge and therapeutic strategies.

In summary, TEX264 Gene Knockout Cell Lines represent a significant advancement for both researchers and clinicians alike, offering unprecedented opportunities to dissect gene function with accuracy and reliability. With a commitment to innovation and excellence, our company specializes in developing and providing state-of-the-art biological products that empower the scientific community to tackle some of the most pressing challenges in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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