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TEX15 Knockout Cell Lines

Gene: TEX15

Official Full Name: testis expressed 15, meiosis and synapsis associatedprovided by HGNC

Gene Summary: This gene encodes a protein that is required for DNA double-strand break repair, chromosome synapsis, and meiotic recombination in spermatocytes. Male mice with a knockout of the orthologous gene are viable but sterile. Loss-of-function mutations in the orthologous mouse gene cause early meiotic arrest in spermatocytes, before the mid-pachytene stage. Naturally occurring mutations in this gene are associated with nonobstructive azoospermia. [provided by RefSeq, Apr 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13454 TEX15 Knockout cell line (HEK293) Human TEX15 1:3~1:6 Negative Online Inquiry

Background

TEX15 Gene Knockout Cell Lines are specialized genetic constructs designed to disable the TEX15 gene, which is critical for spermatogenesis and the maintenance of male fertility. These engineered cell lines serve as essential tools for understanding the functional roles of TEX15 in cellular processes and its implications in reproductive biology. By utilizing powerful genome-editing technologies such as CRISPR-Cas9, these cell lines demonstrate precise gene knockout capabilities, enabling researchers to investigate the downstream effects of gene dysregulation.

The primary function of TEX15 Gene Knockout Cell Lines is to facilitate the study of TEX15's involvement in gamete development and stem cell maintenance. Specifically, disruption of the TEX15 gene is expected to elucidate mechanisms associated with male infertility and contribute to the identification of potential therapeutic targets for related conditions. By creating an environment where the expression of TEX15 is absent, researchers can closely monitor cellular responses, gene expression patterns, and phenotypic outcomes that are pivotal in reproductive health studies.

In the realm of scientific research, these knockout cell lines hold substantial importance as they allow for the exploration of gene function in a controlled setting. Their applications extend to academia and industry, offering insights that can drive advancements in reproductive medicine and fertility treatments. Compared to traditional approaches, such as transient transfection or chemical inhibitors, TEX15 Gene Knockout Cell Lines provide unparalleled specificity and reliability, ensuring that any observed effects are conclusively attributable to the gene of interest.

The unique selling point of our TEX15 Gene Knockout Cell Lines rests in their validated performance and high-quality assurance provided by our dedicated research and development team. Researchers and clinicians will appreciate the convenience of ready-to-use cell lines, enabling rapid experimental setups and a significant reduction in time and resources typically associated with gene knockout experiments.

Our commitment to providing advanced biological products is epitomized by our deep understanding of gene-editing technologies and their applications. With our expertise, we aim to empower researchers and clinicians alike, making valuable contributions to their scientific pursuits and the advancement of human health.

Please note that all services are for research use only. Not intended for any clinical use.

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