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TEN1 Knockout Cell Lines

Gene: TEN1

Official Full Name: TEN1 subunit of CST complexprovided by HGNC

Gene Summary: C17ORF106, or TEN1, appears to function in a telomere-associated complex with STN1 (OBFC1; MIM 613128) and CTC1 (C17ORF68; MIM 613129) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13480 TEN1 Knockout cell line (HeLa) Human TEN1 1:3~1:6 Negative Online Inquiry
KO13481 TEN1 Knockout cell line (HCT 116) Human TEN1 1:2~1:4 Negative Online Inquiry
KO13482 TEN1 Knockout cell line (HEK293) Human TEN1 1:3~1:6 Negative Online Inquiry
KO13483 TEN1 Knockout cell line (A549) Human TEN1 1:3~1:4 Negative Online Inquiry

Background

TEN1 Gene Knockout Cell Lines are a sophisticated biological tool designed to facilitate advanced research in gene function and cellular mechanisms. These cell lines have been genetically modified to exhibit a complete knockout of the TEN1 gene, which is known to play a crucial role in various cellular processes, including DNA repair, cell cycle regulation, and response to stress. By providing a stable genetic background where the TEN1 gene is absent, researchers can effectively investigate the consequences of its loss, allowing for detailed insights into its biological functions.

The primary mechanism through which the TEN1 knockout influences cellular behavior involves the disruption of protein interactions normally facilitated by the TEN1 protein, leading to altered cellular dynamics and phenotypic changes. These cell lines enable researchers to study the implications of TEN1 loss on cellular pathways, including those involved in cancer progression and age-related diseases, making them an invaluable asset in translational research and drug development.

Scientifically, the TEN1 gene has gained significant attention for its potential as a therapeutic target, and these knockout cell lines serve as a critical resource for both basic and applied research, including the development of gene therapy strategies and personalized medicine. Compared to conventional cell lines that retain functional TEN1, our knockout versions allow for precise experimentation that can yield more reliable and reproducible results.

What sets our TEN1 Gene Knockout Cell Lines apart from alternatives on the market is their rigorously validated genetic modification, ensuring the complete and stable gene invalidation. Additionally, they are derived from widely used background cell lines, which facilitates their integration into existing research protocols.

For researchers and clinicians, the ability to assess genetic influences and potential therapeutic interventions in a controlled environment underscores the immense value these cell lines bring to the scientific community. By choosing our TEN1 Gene Knockout Cell Lines, labs can accelerate their research timelines, enhance the quality of their data, and deepen their understanding of critical biological processes.

As a leader in the field of biological products, our company is committed to delivering high-quality, rigorously tested cell lines that empower researchers to explore innovative solutions in genetics, cell biology, and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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