TDG Knockout Cell Lines

Gene: TDG

Official Full Name: thymine DNA glycosylaseprovided by HGNC

Gene Summary: The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]

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Products

Catalog Number	Product Name	Species	Gene	Passage ratio	Mycoplasma testing	Price
KOA13405	TDG Knockout cell line (AC16)	Human	TDG	1：3-1：4	negative	Online Inquiry
KOA28845	TDG Knockout cell line (BEAS-2B)	Human	TDG	1:3~1:4	negative	Online Inquiry
KOA44282	TDG Knockout cell line (U-2932)	Human	TDG	1：2-1：4	negative	Online Inquiry
KOA59663	TDG Knockout cell line (TPC-1)	Human	TDG	1:5-1:8	negative	Online Inquiry
KOA75086	TDG Knockout cell line (NCM460)	Human	TDG	1:2~1:3	negative	Online Inquiry

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