Gene: TCL1A
Official Full Name: TCL1 family AKT coactivator Aprovided by HGNC
Gene Summary: Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]
| Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
|---|---|---|---|---|---|---|
| KOA12910 | TCL1A Knockout cell line (AC16) | Human | TCL1A | 1:3-1:4 | negative | Online Inquiry |
| KOA28351 | TCL1A Knockout cell line (BEAS-2B) | Human | TCL1A | 1:3~1:4 | negative | Online Inquiry |
| KOA43786 | TCL1A Knockout cell line (U-2932) | Human | TCL1A | 1:2-1:4 | negative | Online Inquiry |
| KOA59166 | TCL1A Knockout cell line (TPC-1) | Human | TCL1A | 1:5-1:8 | negative | Online Inquiry |
| KOA74591 | TCL1A Knockout cell line (NCM460) | Human | TCL1A | 1:2~1:3 | negative | Online Inquiry |
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