Gene: TCEAL8
Official Full Name: transcription elongation factor A like 8provided by HGNC
Gene Summary: This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23631 | TCEAL8 Knockout cell line (HeLa) | Human | TCEAL8 | 1:3~1:6 | Negative | Online Inquiry |
KO23632 | TCEAL8 Knockout cell line (HCT 116) | Human | TCEAL8 | 1:2~1:4 | Negative | Online Inquiry |
KO23633 | TCEAL8 Knockout cell line (HEK293) | Human | TCEAL8 | 1:3~1:6 | Negative | Online Inquiry |
KO23634 | TCEAL8 Knockout cell line (A549) | Human | TCEAL8 | 1:3~1:4 | Negative | Online Inquiry |
TCEAL8 Gene Knockout Cell Lines are genetically modified cell lines designed specifically to disable the expression of the TCEAL8 gene, which encodes a member of the TEA/ATTS transcription factor family. These cell lines are crucial tools for researchers interested in understanding the biological functions, signaling pathways, and potential roles of TCEAL8 in health and disease. By utilizing CRISPR/Cas9 technology or other gene-editing methodologies, the TCEAL8 structure is interrupted, allowing for the study of its interactions and effects in various cellular contexts.
The key function of the TCEAL8 Knockout Cell Lines lies in their ability to elucidate the gene's role in processes such as cell growth, differentiation, and apoptosis, as well as its potential involvement in oncogenic pathways. These tools enable scientists to perform comparative analyses with wild-type cell lines, thereby providing insight into how the absence of TCEAL8 affects cellular behavior and gene expression profiles. This information is invaluable for both basic research and potential translational applications in the development of targeted therapies.
In clinical and research settings, these knockout cell lines serve as models for understanding complex diseases, including cancers where TCEAL8 may play a role. By using these advanced cell lines, researchers can accelerate their investigations into therapeutic interventions and enhance the development of personalized medicine approaches.
The unique advantage of TCEAL8 Gene Knockout Cell Lines over other models is their specificity and precision in gene targeting, reducing off-target effects commonly associated with older gene-editing techniques. Additionally, these lines can be used in a variety of experimental systems, making them versatile tools for laboratories.
Overall, the value of TCEAL8 Gene Knockout Cell Lines to researchers and clinicians lies in their potential to provide deeper insights into gene functionalities, contributing to the advancement of scientific knowledge and innovative therapies. Our company prides itself on its expertise in delivering high-quality biological products that empower research and drive discovery, ensuring that our customers have the best tools available to meet their scientific challenges.
Please note that all services are for research use only. Not intended for any clinical use.
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