Gene: TCAP
Official Full Name: titin-capprovided by HGNC
Gene Summary: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34047 | TCAP Knockout cell line (HEK293) | Human | TCAP | 1:3~1:6 | Negative | Online Inquiry |
TCAP Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to provide researchers with tools for studying the function of the TCAP gene, which encodes for a protein involved in various physiological processes. These cell lines have been cultivated to feature targeted deletions or "knockouts" of the TCAP gene, enabling scientists to investigate the gene's role in cellular pathways, disease mechanisms, and potential therapeutic interventions.
The primary function of TCAP Gene Knockout Cell Lines lies in their ability to facilitate functional genomics studies. By eliminating the expression of the TCAP protein, researchers can observe the resulting phenotypic changes, which provides crucial insights into how the gene influences cellular behavior and interactions. This model serves as a vital resource for understanding the contributions of the TCAP gene in conditions such as cardiomyopathies and other muscle-related disorders.
The scientific significance of these cell lines extends to applications in both basic research and clinical settings. Their use in drug discovery enables researchers to identify potential therapeutic targets and assess the efficacy of novel pharmacological agents while observing the consequences of TCAP gene loss. Additionally, these models can aid in the validation of biomarkers related to various diseases, enhancing the development of precision medicine approaches.
One of the unique selling points of TCAP Gene Knockout Cell Lines is their high specificity and reproducibility, ensuring reliable data generation over time. Compared to alternative models like CRISPR/Cas9 modified cells that may yield off-target effects, these knockout lines are derived from a thorough validation process, providing confidence in their application for critical research.
For researchers and clinicians, the value of TCAP Gene Knockout Cell Lines lies in their ability to uncover novel insights, drive innovative therapeutic strategies, and ultimately contribute to the ongoing efforts to combat gene-related diseases. Our company boasts extensive experience in creating high-quality biological products, ensuring that our offerings are backed by rigorous science and tailored to meet the needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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