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TBKBP1 Knockout Cell Lines

Gene: TBKBP1

Official Full Name: TBK1 binding protein 1provided by HGNC

Gene Summary: TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway (Bouwmeester et al., 2004 [PubMed 14743216]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05572 TBKBP1 Knockout cell line (HeLa) Human TBKBP1 1:3~1:6 Negative Online Inquiry
KO05573 TBKBP1 Knockout cell line (HCT 116) Human TBKBP1 1:2~1:4 Negative Online Inquiry
KO05574 TBKBP1 Knockout cell line (HEK293) Human TBKBP1 1:3~1:6 Negative Online Inquiry
KO05575 TBKBP1 Knockout cell line (A549) Human TBKBP1 1:3~1:4 Negative Online Inquiry

Background

TBKBP1 Gene Knockout Cell Lines are advanced genetically engineered cell models that have been specifically designed to study the role of the TBKBP1 gene in various biological processes and disease states. TBKBP1 (TANK-binding kinase 1 binding protein 1) is known to play a crucial role in cellular responses to stress, including the innate immune response and autophagy regulation. By knocking out this gene, researchers can elucidate its functions and interactions in critical pathways, providing valuable insights into gene-related mechanisms of disease.

The key function of TBKBP1 Gene Knockout Cell Lines lies in their ability to serve as a controlled platform for investigating the impact of TBKBP1 deletion on cellular behavior, signaling pathways, and phenotypic changes. The knockout technology includes CRISPR-Cas9 or other gene editing methods, ensuring precise alterations and reproducibility in experiments. Researchers utilize these cell lines to assess the gene's contribution to various conditions, including autoimmune disorders, neurodegenerative diseases, and cancer research.

The scientific importance of using TBKBP1 Gene Knockout Cell Lines extends into diverse research and clinical settings. By offering a method to dissect the biological roles of TBKBP1, these cell lines enhance the understanding of complex disease mechanisms and facilitate the identification of potential therapeutic targets. Their utility in high-throughput screening and drug discovery processes makes them invaluable for medicinal chemistry and translational research.

Compared to alternative models, TBKBP1 Gene Knockout Cell Lines offer unparalleled specificity and reliability in studying gene function and interaction effects. While conventional models may introduce variability, our products ensure consistent knockout efficiency, thereby increasing the confidence in experimental outcomes. These models also streamline the experimental design, saving time and resources during investigation phases.

By providing scientifically validated and meticulously characterized TBKBP1 Gene Knockout Cell Lines, we cater to the essential needs of researchers and clinicians aiming to advance their studies in immunity, cell biology, and disease pathology. Our company's expertise in genetic engineering and commitment to quality ensures that our offerings empower scientists to achieve groundbreaking discoveries in their respective fields.

Please note that all services are for research use only. Not intended for any clinical use.

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