Gene: TBC1D8
Official Full Name: TBC1 domain family member 8provided by HGNC
Gene Summary: Predicted to enable GTPase activator activity. Predicted to be involved in blood circulation and positive regulation of cell population proliferation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31181 | TBC1D8 Knockout cell line (HeLa) | Human | TBC1D8 | 1:3~1:6 | Negative | Online Inquiry |
KO31182 | TBC1D8 Knockout cell line (HCT 116) | Human | TBC1D8 | 1:2~1:4 | Negative | Online Inquiry |
KO31183 | TBC1D8 Knockout cell line (HEK293) | Human | TBC1D8 | 1:3~1:6 | Negative | Online Inquiry |
KO31184 | TBC1D8 Knockout cell line (A549) | Human | TBC1D8 | 1:3~1:4 | Negative | Online Inquiry |
TBC1D8 Gene Knockout Cell Lines are genetically modified cell lines designed to have a targeted deletion of the TBC1D8 gene, which encodes a protein known to be involved in the regulation of cellular signaling pathways and membrane dynamics. These cell lines are essential tools for researchers studying the functional role of TBC1D8 in various biological processes, including cellular metabolism, autophagy, and intracellular trafficking. By systematically eliminating the activities of the TBC1D8 gene, researchers can dissect its contribution to cellular physiology and pathology.
The primary function of TBC1D8 is its involvement in the regulation of RAB GTPases, crucial molecular switches that govern intracellular transport and organelle dynamics. The knockout of TBC1D8 leads to altered vesicle trafficking and impacts metabolic signaling, thus facilitating studies on diseases related to these pathways, including cancer and metabolic disorders. These cell lines serve as a powerful platform for elucidating the cellular mechanisms underlying TBC1D8, allowing for high-resolution studies of its role in various physiological and pathological contexts.
In research and clinical settings, TBC1D8 Gene Knockout Cell Lines are invaluable for scientists focused on unraveling the complexities of cellular communication and trafficking. The ability to study the loss of TBC1D8 function in a controlled environment enables meaningful insights into translational medicine, particularly for developing targeted therapies and diagnostics.
Compared to alternative models, such as transient transfection or RNA interference methods, these knockout cell lines offer a more stable and consistent approach to study gene function over prolonged periods. This stability is crucial for long-term experiments and the reproducibility of results, significantly enhancing the quality of data produced.
For researchers and clinicians, the availability of TBC1D8 Gene Knockout Cell Lines not only accelerates discovery but also empowers innovative approaches in therapeutic development. Each cell line is meticulously characterized and validated, reflecting our commitment to the highest scientific standards.
Our company prides itself on its expertise in generating high-quality genetic tools that enable groundbreaking research. With a focus on delivering well-defined products, we support the scientific community in advancing knowledge and translating findings into impactful therapies.
Please note that all services are for research use only. Not intended for any clinical use.
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