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TBC1D19 Knockout Cell Lines

Gene: TBC1D19

Official Full Name: TBC1 domain family member 19provided by HGNC

Gene Summary: Predicted to enable GTPase activator activity. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13539 TBC1D19 Knockout cell line (HeLa) Human TBC1D19 1:3~1:6 Negative Online Inquiry
KO13540 TBC1D19 Knockout cell line (HCT 116) Human TBC1D19 1:2~1:4 Negative Online Inquiry
KO13541 TBC1D19 Knockout cell line (HEK293) Human TBC1D19 1:3~1:6 Negative Online Inquiry
KO13542 TBC1D19 Knockout cell line (A549) Human TBC1D19 1:3~1:4 Negative Online Inquiry

Background

TBC1D19 gene knockout cell lines represent a groundbreaking tool in genetic research, specifically designed to help elucidate the biological functions of the TBC1D19 gene, which is implicated in various cellular processes, including autophagy and vesicle trafficking. By creating cell lines in which the TBC1D19 gene has been systematically disrupted, researchers can investigate the downstream effects of its absence, enabling a clearer understanding of its role in normal and pathological states.

The key function of TBC1D19 knockout cell lines is to provide a controlled environment where the effects of the gene's loss can be scrutinized. This is achieved using CRISPR/Cas9 technology to ensure precision in gene editing. As TBC1D19 is associated with cellular homeostasis and has ties to neurodegenerative diseases, these cell lines serve as invaluable models for studying the gene's contributions to cell signaling pathways and potential mechanisms of disease.

From a scientific perspective, these knockout cell lines are fundamental for advancing research in neurobiology, cell biology, and gene therapy. They can be employed in high-throughput screening assays to identify compounds that may rescue the phenotypic manifestations caused by the absence of TBC1D19. Furthermore, they provide a robust platform for validating therapeutics aimed at modulating the pathways influenced by TBC1D19, thus bridging translational research with clinical applications.

Advantages of TBC1D19 gene knockout cell lines lie in their specificity and usability; they offer a unique opportunity to focus on the TBC1D19 gene without the confounding effects often observed in whole-organism studies. Compared to other gene-editing tools, the precision of CRISPR/Cas9 minimizes off-target effects, providing researchers with greater confidence in their findings.

For researchers and clinicians, the value of TBC1D19 knockout cell lines is clear: they facilitate deeper insights into disease mechanisms, paving the way for innovative therapeutic strategies. Additionally, these cell lines can serve as a reliable reference point in studies aimed at understanding gene function in the context of disease.

At our company, we pride ourselves on our commitment to providing high-quality biological products that empower researchers in their quest for knowledge and innovation. Our expertise in genetic engineering and cell line development ensures that our TBC1D19 gene knockout cell lines meet rigorous scientific standards, making them essential tools in the field of genetic research.

Please note that all services are for research use only. Not intended for any clinical use.

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