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TATDN2 Knockout Cell Lines

Gene: TATDN2

Official Full Name: TatD DNase domain containing 2provided by HGNC

Gene Summary: Predicted to enable metal ion binding activity and nuclease activity. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32743 TATDN2 Knockout cell line (HeLa) Human TATDN2 1:3~1:6 Negative Online Inquiry
KO32744 TATDN2 Knockout cell line (HCT 116) Human TATDN2 1:2~1:4 Negative Online Inquiry
KO32745 TATDN2 Knockout cell line (HEK293) Human TATDN2 1:3~1:6 Negative Online Inquiry
KO32746 TATDN2 Knockout cell line (A549) Human TATDN2 1:3~1:4 Negative Online Inquiry

Background

TATDN2 Gene Knockout Cell Lines represent a vital tool in biomedical research that facilitates the study of the TATDN2 gene, involved in various cellular processes, including transcription regulation and RNA metabolism. These cell lines are genetically engineered to have the TATDN2 gene disrupted, enabling researchers to elucidate the gene's specific functions and its role in disease pathology.

The key mechanism of these knockout cell lines involves a precise gene editing technique, most commonly CRISPR/Cas9, which introduces targeted mutations, leading to a complete loss of function of the TATDN2 gene. This allows scientists to investigate the gene's effects on cellular behavior, signaling pathways, and molecular interactions without the confounding influences of TATDN2 expression, thus providing a clearer understanding of its biological relevance.

These cell lines hold significant scientific importance, particularly in research focused on cancer biology, neurodevelopmental disorders, and cellular stress responses, where the role of TATDN2 is being actively explored. In clinical settings, these knockouts can serve as model systems for testing therapeutic strategies aimed at diseases associated with TATDN2 dysregulation, making them instrumental in the validation of potential drug targets.

One of the unique selling points of TATDN2 Gene Knockout Cell Lines is their ability to provide reproducible and reliable results compared to transient knockdown methods, which can lead to variability and less precise data. Additionally, as permanently altered cell lines, they can be easily cultured, expanded, and utilized in a variety of downstream applications, such as drug screening, gene expression analysis, and functional assays.

For researchers and clinicians, investing in TATDN2 Gene Knockout Cell Lines means gaining access to a robust platform for groundbreaking studies that could unveil novel mechanisms of disease and pave the way for innovative therapeutic interventions. Our company prides itself on offering exceptional quality and rigorously validated biological products, backed by our commitment to advancing scientific discovery and supporting the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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