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TAPT1 Knockout Cell Lines

Gene: TAPT1

Official Full Name: transmembrane anterior posterior transformation 1provided by HGNC

Gene Summary: This gene encodes a highly conserved protein that localizes to the centrosome and/or ciliary basal body. Mutations in this gene disrupt Golgi morphology and trafficking and normal primary cilium formation and these mutations are congenitally manifested by severe undermineralization of the intra-uterine skeleton. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. In mouse, this gene is thought to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. [provided by RefSeq, Jan 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00124 TAPT1 Knockout cell line (HEK293) Human TAPT1 1:3~1:6 Negative Online Inquiry
KO37007 TAPT1 Knockout cell line (HeLa) Human TAPT1 1:3~1:6 Negative Online Inquiry
KO37008 TAPT1 Knockout cell line (HCT 116) Human TAPT1 1:2~1:4 Negative Online Inquiry

Background

TAPT1 Gene Knockout Cell Lines represent cutting-edge biological tools generated through precise gene editing techniques, specifically CRISPR/Cas9 technology. These cell lines have been meticulously engineered to disrupt the TAPT1 gene, allowing researchers to investigate the gene’s function and contribution to various cellular processes, such as proliferation, differentiation, and response to stress. By creating a knockout model, scientists can precisely observe the phenotypic consequences of gene loss, offering insights into its biological roles and potential implications in diseases.

The primary function of TAPT1 Gene Knockout Cell Lines is to serve as a platform for functional genomics studies. With a complete absence of TAPT1 protein, these specific cell lines facilitate detailed investigations into cellular metabolism, signal transduction pathways, and the molecular mechanisms underlying diseases such as cancer and neurodegeneration. Through phenotypic analyses, researchers can assess alterations in behavior, morphology, and response to therapeutic agents, thereby elucidating TAPT1's role in health and disease.

The scientific importance of these cell lines extends to their application in both research and clinical settings. They provide a reliable model for drug discovery, enabling the examination of possible therapeutic targets and the identification of biomarkers for disease diagnostics. Additionally, they can be utilized in high-throughput screening assays, fostering innovations in precision medicine and personalized therapies.

What sets TAPT1 Gene Knockout Cell Lines apart from other gene-editing alternatives is their validated knockout efficiency and consistent performance across various experimental conditions. These cell lines are backed by extensive quality control measures and come with comprehensive technical support, ensuring that users can seamlessly integrate them into their research workflows. Furthermore, their specificity enhances experimental reliability, providing a unique advantage for researchers aiming to dissect complex biological processes.

For researchers and clinicians committed to advancing their understanding of gene function and disease mechanisms, TAPT1 Gene Knockout Cell Lines epitomize an indispensable resource. They empower the scientific community to explore uncharted domains of molecular biology, fostering breakthroughs with far-reaching implications.

As leaders in the development of innovative biological products, our company is dedicated to providing high-quality gene-editing tools that equip researchers to push the boundaries of their studies, facilitating groundbreaking discoveries that can transform clinical practices.

Please note that all services are for research use only. Not intended for any clinical use.

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