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TAOK3 Knockout Cell Lines

Gene: TAOK3

Official Full Name: TAO kinase 3provided by HGNC

Gene Summary: The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases. [provided by RefSeq, Oct 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO10465 TAOK3 Knockout cell line (HeLa) Human TAOK3 1:3~1:6 Negative Online Inquiry
KO10466 TAOK3 Knockout cell line (HCT 116) Human TAOK3 1:2~1:4 Negative Online Inquiry
KO10467 TAOK3 Knockout cell line (HEK293) Human TAOK3 1:3~1:6 Negative Online Inquiry
KO10468 TAOK3 Knockout cell line (A549) Human TAOK3 1:3~1:4 Negative Online Inquiry

Background

TAOK3 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the TAOK3 gene, known for its pivotal role in various cellular processes, including cell proliferation, differentiation, and response to stress. By employing CRISPR/Cas9 technology, these knockout lines enable precise disruption of the TAOK3 gene, allowing researchers to explore its function and regulation in both normal and pathological states.

The primary function of TAOK3 Gene Knockout Cell Lines is to provide a controlled environment to assess the downstream effects of TAOK3 gene disruption. These models enable scientists to dissect the molecular pathways influenced by TAOK3, contributing to a better understanding of its implications in cancer biology, neurodegenerative diseases, and metabolic disorders. The knockout cell lines serve as a critical tool for elucidating how TAOK3 affects cellular signaling pathways, interaction with other genes, and impacts on overall cellular health.

In scientific research and clinical settings, the ability to analyze the knockout of specific genes like TAOK3 has profound significance. It allows for the identification of potential therapeutic targets and the development of innovative treatment strategies. The utility of these cell lines extends to drug discovery, where researchers can screen compounds for efficacy against cells lacking functional TAOK3, thereby pinpointing new avenues for intervention.

What sets TAOK3 Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Traditional methods of gene disruption often result in off-target effects, leading to ambiguous interpretations. In contrast, our knockout cell lines are validated for specificity, ensuring that the observed phenotypes can be confidently attributed to the loss of TAOK3 function. This reliability accelerates the research process and enhances the reproducibility of results, key factors for securing funding and publishing high-impact findings.

For researchers, clinicians, and biopharmaceutical companies, the availability of TAOK3 Gene Knockout Cell Lines is invaluable. They represent a significant advancement in the toolbox of modern molecular biology, offering a streamlined approach to understanding gene function and disease mechanisms. By providing high-quality, reliable cell lines, we aim to empower the scientific community to innovate and advance therapies targeting complex diseases associated with TAOK3.

With expertise in the development of cutting-edge biological products, our company is dedicated to supporting researchers and clinicians alike. We deliver tools that enhance the understanding of complex genetic interactions, contributing to the ongoing pursuit of biomedical breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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