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TAOK2 Knockout Cell Lines

Gene: TAOK2

Official Full Name: TAO kinase 2provided by HGNC

Gene Summary: Enables mitogen-activated protein kinase kinase binding activity; neuropilin binding activity; and protein serine/threonine kinase activity. Involved in several processes, including focal adhesion assembly; intracellular signal transduction; and positive regulation of MAPK cascade. Located in cytoplasmic vesicle; cytosol; and nuclear lumen. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO10469 TAOK2 Knockout cell line (HeLa) Human TAOK2 1:3~1:6 Negative Online Inquiry
KO10470 TAOK2 Knockout cell line (HCT 116) Human TAOK2 1:2~1:4 Negative Online Inquiry
KO10471 TAOK2 Knockout cell line (HEK293) Human TAOK2 1:3~1:6 Negative Online Inquiry
KO10472 TAOK2 Knockout cell line (A549) Human TAOK2 1:3~1:4 Negative Online Inquiry

Background

TAOK2 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the functional role of the TAOK2 gene, a serine/threonine kinase implicated in various cellular processes, including stress response, cellular signaling, and cytoskeletal dynamics. These knockout cell lines are generated using advanced CRISPR/Cas9 technology, ensuring precise deletion of the TAOK2 gene, thereby allowing researchers to observe the phenotypic and biochemical changes that result from its absence.

The primary function of TAOK2 is to modulate signaling pathways related to cellular stress and apoptosis, particularly in response to DNA damage. By utilizing these knockout cell lines, researchers can delve deeper into the downstream effects of TAOK2 loss, providing insights into its contributions to disease states, including neurodegenerative disorders and cancer. The knockout models are invaluable in understanding cellular mechanisms and developing potential therapeutic strategies aimed at diseases where TAOK2 is a critical regulatory factor.

One of the major advantages of TAOK2 Gene Knockout Cell Lines is their potential to replicate the physiological environment of human cells, offering a more relevant context for studies compared to traditional two-dimensional culture systems. Their availability enhances the research community's ability to conduct high-throughput screening and drug discovery efforts targeting TAOK2-related pathways. Additionally, these knockout cell lines provide a unique opportunity to study compensatory mechanisms that may arise from the loss of TAOK2, allowing researchers to identify alternative pathways that could be therapeutically targeted.

The value of TAOK2 Gene Knockout Cell Lines lies in their capability to yield reproducible and robust data, essential for advancing our understanding of cellular processes and disease mechanisms. By integrating these innovative models into their research, scientists and clinicians can significantly accelerate their findings, paving the way for novel treatment approaches.

With extensive expertise in genetic engineering and cellular biology, our company is committed to supporting the research community by providing high-quality biological products tailored for groundbreaking discoveries. Our dedication to excellence ensures that researchers can rely on us for their critical experimentation needs.

Please note that all services are for research use only. Not intended for any clinical use.

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