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TAOK1 Knockout Cell Lines

Gene: TAOK1

Official Full Name: TAO kinase 1provided by HGNC

Gene Summary: Enables alpha-tubulin binding activity; beta-tubulin binding activity; and kinase activity. Involved in several processes, including mitotic G2 DNA damage checkpoint signaling; negative regulation of microtubule depolymerization; and positive regulation of MAPK cascade. Located in microtubule cytoskeleton and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13588 TAOK1 Knockout cell line (HeLa) Human TAOK1 1:3~1:6 Negative Online Inquiry
KO13589 TAOK1 Knockout cell line (HCT 116) Human TAOK1 1:2~1:4 Negative Online Inquiry
KO13590 TAOK1 Knockout cell line (HEK293) Human TAOK1 1:3~1:6 Negative Online Inquiry
KO13591 TAOK1 Knockout cell line (A549) Human TAOK1 1:3~1:4 Negative Online Inquiry

Background

TAOK1 Gene Knockout Cell Lines are specifically engineered cellular models that have undergone precise genetic modification to inactivate the TAOK1 gene. This gene encodes a serine/threonine kinase that plays a pivotal role in various cellular processes, including mitosis, cell growth, and responses to stress signals. By knocking out TAOK1, these cell lines provide researchers with valuable insights into the gene’s function, its involvement in developmental biology, and its implications in diseases such as cancer and neurodegenerative disorders.

The key mechanism behind these knockout cell lines involves the use of cutting-edge CRISPR-Cas9 gene-editing technology, which allows for targeted disruptions of the TAOK1 gene, leading to a complete absence of its protein product. As a result, scientists can dissect the contributions of TAOK1 to cellular pathways and elucidate its function in different physiological contexts. This capability is essential for advancing our understanding of the molecular mechanisms that underpin various diseases.

In research and clinical settings, the TAOK1 Gene Knockout Cell Lines serve as crucial tools for functional genomics, drug discovery, and the development of novel therapeutic strategies. By employing these models, researchers can investigate the downstream effects of TAOK1 knockout on cellular signaling pathways, gene expression profiles, and overall cellular behavior, facilitating the identification of potential drug targets and biomarkers.

What sets our TAOK1 Gene Knockout Cell Lines apart from alternatives is their high specificity, reproducibility, and robust validation through rigorous quality control measures. Each cell line has been characterized extensively, ensuring that users receive reliable data for their experiments. Furthermore, our team offers comprehensive support and expertise in experimental design and data interpretation, enabling users to maximize the potential of these valuable resources.

Researchers and clinicians alike will find immense value in our TAOK1 Gene Knockout Cell Lines, as they bridge the gap between basic research and translational applications. With a focus on quality and innovation, our company remains a trusted partner in the realm of genetic research, dedicated to equipping the scientific community with the tools necessary to unlock biological mysteries and improve patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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