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TAFA2 Knockout Cell Lines

Gene: TAFA2

Official Full Name: TAFA chemokine like family member 2provided by HGNC

Gene Summary: This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13593 TAFA2 Knockout cell line (HeLa) Human TAFA2 1:3~1:6 Negative Online Inquiry
KO13594 TAFA2 Knockout cell line (HCT 116) Human TAFA2 1:2~1:4 Negative Online Inquiry

Background

TAFA2 Gene Knockout Cell Lines are genetically engineered cell lines designed specifically to study the functional implications of the TAFA2 gene, which has been implicated in various biological processes, including inflammation and neurodevelopment. These knockout cell lines allow researchers to observe the phenotypic and molecular changes that occur in the absence of TAFA2, providing a critical tool for elucidating its role in health and disease.

The primary function of TAFA2 Gene Knockout Cell Lines involves the complete inactivation of the TAFA2 gene, resulting in the abrogation of its protein product, which interacts with specific receptors involved in neuronal signaling and immune responses. By utilizing techniques such as CRISPR-Cas9 gene editing, these cell lines enable precise modifications at the genomic level, leading to an enhanced understanding of the pathways in which TAFA2 is involved, as well as its potential contributions to pathological states such as neurodegenerative disorders and autoimmune diseases.

The scientific importance of these knockout cell lines is underscored by their applications in both research and clinical settings. They serve as invaluable models for drug discovery, enabling researchers to screen for compounds that can modulate TAFA2-related pathways, potentially leading to novel therapeutic strategies. Furthermore, by studying these cell lines, researchers can gain insights into the gene's involvement in various cellular processes, thus aiding in the development of targeted interventions.

What sets our TAFA2 Gene Knockout Cell Lines apart from competitors is the rigorous validation of their knockout status through genome sequencing and phenotypic characterization. The consistency and reliability of these models reduce variability in experimental results, providing researchers with confidence in their findings. Additionally, our cell lines come with optimized growth protocols and detailed handling guidelines, ensuring ease of use for researchers from diverse backgrounds.

For researchers and clinicians aiming to delve deeper into the biological roles of TAFA2, these knockout cell lines represent a significant advancement in available tools. They are not only a gateway to understanding complex biological interactions but also pave the way for potential breakthroughs in therapeutic contexts.

Our company has a strong commitment to advancing biological research through innovative products and solutions. With a focus on quality, reproducibility, and support, we aim to empower scientists in their quest for discovery, making our TAFA2 Gene Knockout Cell Lines an essential addition to any research laboratory.

Please note that all services are for research use only. Not intended for any clinical use.

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