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TACC2 Knockout Cell Lines

Gene: TACC2

Official Full Name: transforming acidic coiled-coil containing protein 2provided by HGNC

Gene Summary: Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03793 TACC2 Knockout cell line (HeLa) Human TACC2 1:3~1:6 Negative Online Inquiry
KO03794 TACC2 Knockout cell line (HCT 116) Human TACC2 1:2~1:4 Negative Online Inquiry
KO03795 TACC2 Knockout cell line (HEK293) Human TACC2 1:3~1:6 Negative Online Inquiry
KO03796 TACC2 Knockout cell line (A549) Human TACC2 1:3~1:4 Negative Online Inquiry

Background

TACC2 Gene Knockout Cell Lines are advanced biological tools designed for the study of the TACC2 (Transforming Acidic Coiled-Coil 2) gene, which plays a crucial role in mitotic spindle assembly and cell cycle regulation. The cell lines are genetically modified to disrupt the expression of the TACC2 gene, allowing researchers to investigate its functional significance in cellular processes, tumorigenesis, and developmental biology.

The primary function of TACC2 Gene Knockout Cell Lines is to facilitate the exploration of the consequences of TACC2 gene loss, providing insights into the pathways it influences. By observing the phenotypic changes in these cell lines, scientists can elucidate mechanisms involved in cell division and cancer progression. Additionally, these knockout models are invaluable in screening for therapeutic targets, understanding drug resistance, and studying the cellular response to various stressors, making them essential tools in both basic and applied biomedical research.

The scientific importance of TACC2 Gene Knockout Cell Lines lies in their applications in cancer research and stem cell studies. Researchers can employ these cell lines to unveil potential biomarkers for cancer progression or evaluate the efficacy of novel therapeutic agents. Compared to other genetic models, these knockout cell lines offer a more specific and precise approach to dissecting the role of TACC2, minimizing off-target effects common with alternative gene-editing strategies.

What truly sets TACC2 Gene Knockout Cell Lines apart is their ability to provide researchers with reproducible and measurable results in real-time cell behavior under controlled experimental conditions. This creates a robust platform for generating high-quality data that can lead to significant scientific breakthroughs.

Our company is dedicated to providing innovative genetic research tools, and our expertise in cell line development ensures that TACC2 Gene Knockout Cell Lines meet the highest standards of quality and reliability, empowering researchers to achieve their scientific goals with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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