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SYNRG Knockout Cell Lines

Gene: SYNRG

Official Full Name: synergin gammaprovided by HGNC

Gene Summary: This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31002 SYNRG Knockout cell line (HeLa) Human SYNRG 1:3~1:6 Negative Online Inquiry
KO31003 SYNRG Knockout cell line (HCT 116) Human SYNRG 1:2~1:4 Negative Online Inquiry
KO31004 SYNRG Knockout cell line (HEK293) Human SYNRG 1:3~1:6 Negative Online Inquiry
KO31005 SYNRG Knockout cell line (A549) Human SYNRG 1:3~1:4 Negative Online Inquiry

Background

SYNRG Gene Knockout Cell Lines are specialized, genetically engineered cells designed to facilitate the study of gene function through the systematic deletion of targeted genes. Employing advanced CRISPR/Cas9 technology, these cell lines are created to provide researchers with a precise and efficient platform for exploring cellular pathways and validating gene-targeting therapeutics. By knocking out specific genes, researchers can better understand gene roles in cellular processes, disease mechanisms, and the effects of genetic alterations on cellular behavior.

The underlying mechanism includes targeted double-strand breaks in the DNA, followed by non-homologous end joining, which results in insertions or deletions that disrupt the gene function. This process allows for the generation of knockout models that are invaluable for investigating gene-specific functions in various biological contexts, including cancer research, metabolic disorders, and pharmacogenomics.

The scientific importance of SYNRG Gene Knockout Cell Lines lies in their wide-ranging applications across research and clinical settings. They serve as essential tools for drug discovery, enabling screening of novel compounds against genetically simplified models, as well as for functional genomics studies that aim to pinpoint gene involvement in disease.

Compared to alternative models, SYNRG's cell lines offer superior customization, with a user-friendly platform that simplifies the creation of knockout models tailored to specific research needs. Additionally, the robustness and reproducibility of the experiments conducted with these cell lines increase the reliability of outcomes, providing a competitive edge for researchers looking to produce publishable results efficiently.

For researchers, clinicians, and pharmaceutical developers, SYNRG Gene Knockout Cell Lines represent a pivotal advancement in genetic research, allowing for high-throughput analysis and reducing the time required to move from hypothesis to experimental validation. With our commitment to innovation and quality, SYNRG stands at the forefront of genetic engineering, providing scientists with the tools they need to unlock the complexities of biology. Our expertise in gene modifications ensures that you receive not only high-quality products but also unparalleled support in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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