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SYNPO2 Knockout Cell Lines

Gene: SYNPO2

Official Full Name: synaptopodin 2provided by HGNC

Gene Summary: Enables alpha-actinin binding activity and filamin binding activity. Involved in positive regulation of actin filament bundle assembly; positive regulation of cell migration; and regulation of Rho-dependent protein serine/threonine kinase activity. Located in several cellular components, including Z disc; focal adhesion; and stress fiber. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13610 SYNPO2 Knockout cell line (A549) Human SYNPO2 1:3~1:4 Negative Online Inquiry

Background

SYNPO2 Gene Knockout Cell Lines are an advanced biological research tool designed to facilitate the study of the SYNPO2 gene, which is known for its role in cellular structure and function, particularly in glomerular podocytes. These custom-engineered cell lines provide researchers with a powerful means to investigate gene function through the elimination of SYNPO2, allowing for in-depth analysis of its involvement in vital biological processes and disease mechanisms.

The key function of the SYNPO2 Gene Knockout Cell Lines lies in their ability to provide a controlled environment in which the impacts of SYNPO2 absence can be observed. Employing CRISPR-Cas9 genome editing technology, these cell lines ensure precise modifications to the target gene, providing highly reproducible results. By studying the phenotypic consequences of SYNPO2 deletion, researchers can glean insights into podocyte biology, renal diseases, and potential therapeutic targets.

The scientific importance of these knockout cell lines extends beyond basic research; they offer invaluable models for understanding pathophysiological conditions such as nephrotic syndrome or diabetes-related kidney damage. Furthermore, they can be utilized in drug discovery and development, enabling the assessment of therapeutic agents that may modulate SYNPO2-related pathways.

What sets SYNPO2 Gene Knockout Cell Lines apart from traditional research models is their specificity and reliability. Given that conventional methods often involve less precise gene manipulation techniques, the SYNPO2 knockout model minimizes off-target effects and enhances the validation of experimental results. This specificity not only accelerates the pace of research but also ensures that findings are robust and meaningful.

Researchers and clinicians will find SYNPO2 Gene Knockout Cell Lines particularly valuable due to their ability to unravel complex genetic interactions and to provide a clearer understanding of disease mechanisms. Such insights are critical in developing novel therapeutic strategies to combat kidney diseases related to SYNPO2 dysfunction.

Our company prides itself on its expertise in developing high-quality biological products that meet the needs of the scientific community. With a commitment to innovation and excellence, we strive to empower researchers to advance their understanding of genetics and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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