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SYNM Knockout Cell Lines

Gene: SYNM

Official Full Name: syneminprovided by HGNC

Gene Summary: The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29428 SYNM Knockout cell line (HeLa) Human SYNM 1:3~1:6 Negative Online Inquiry
KO29429 SYNM Knockout cell line (HCT 116) Human SYNM 1:2~1:4 Negative Online Inquiry
KO29430 SYNM Knockout cell line (HEK293) Human SYNM 1:3~1:6 Negative Online Inquiry
KO29431 SYNM Knockout cell line (A549) Human SYNM 1:3~1:4 Negative Online Inquiry

Background

SYNM Gene Knockout Cell Lines are a cutting-edge tool designed for advanced genetic research and functional studies. These cell lines feature specific genes that have been entirely inactivated or "knocked out" using state-of-the-art CRISPR/Cas9 technology. This precise genome editing method enables researchers to analyze the biological roles of target genes with unparalleled accuracy, thereby elucidating their contributions to various cellular processes.

The key function of SYNM Gene Knockout Cell Lines lies in their ability to facilitate studies on gene function, signaling pathways, and potential therapeutic targets. By eliminating the expression of a specific gene, researchers can assess cellular responses to different stimuli, understand the implications of gene loss in disease models, and validate therapeutic compounds that influence gene activity. This capability is vital for both basic research and the development of novel treatment strategies.

In scientific contexts, SYNM Gene Knockout Cell Lines hold significant value for both academic researchers and pharma/biotech industries, enabling cutting-edge investigations into cancer biology, neurogenetics, and metabolic disorders. Their utility extends to drug discovery and development, where understanding gene function can significantly influence the pathway to therapeutic success.

Compared to traditional methods of gene disruption, such as homologous recombination, SYNM Gene Knockout Cell Lines offer a streamlined, efficient, and reproducible approach. They do not require lengthy screening processes, enabling substantial time savings and resource optimization. Additionally, our cell lines come with extensive characterization and validation data, ensuring reproducibility and enhancing trust in the experimental outcomes.

SYNM is committed to propelling scientific discovery and clinical advancements by providing high-quality biological products. Leveraging our expertise in genetics and cell biology, we deliver robust tools that empower researchers and clinicians to unravel complex biological questions and contribute to transformative innovations in healthcare.

Please note that all services are for research use only. Not intended for any clinical use.

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