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SWI5 Knockout Cell Lines

Gene: SWI5

Official Full Name: SWI5 homologous recombination repair proteinprovided by HGNC

Gene Summary: Involved in cellular response to ionizing radiation and double-strand break repair via homologous recombination. Part of Swi5-Sfr1 complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13625 SWI5 Knockout cell line (HeLa) Human SWI5 1:3~1:6 Negative Online Inquiry
KO13626 SWI5 Knockout cell line (HCT 116) Human SWI5 1:2~1:4 Negative Online Inquiry
KO13627 SWI5 Knockout cell line (HEK293) Human SWI5 1:3~1:6 Negative Online Inquiry
KO13628 SWI5 Knockout cell line (A549) Human SWI5 1:3~1:4 Negative Online Inquiry

Background

SWI5 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the SWI5 gene, a critical regulator of cell cycle progression and transcriptional activation in eukaryotic organisms. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines provide researchers with a powerful tool to investigate the functional roles of the SWI5 gene in various biological processes, such as cellular proliferation, differentiation, and response to stress.

The primary function of these knockout cell lines is to allow for the study of gene function and pathway interactions by eliminating the SWI5 gene, thereby facilitating the examination of phenotypic changes that arise from its absence. This can elucidate the consequences of SWI5 misregulation, which is implicated in several diseases, including cancer. The systems in place for monitoring cell viability, proliferation rates, and apoptosis can be expertly employed with the SWI5 knockout lines, offering valuable insights into cellular responses to treatment modalities.

In terms of scientific importance, SWI5 Gene Knockout Cell Lines serve as a vital resource in both basic and applied research settings, including drug development, genetic studies, and functional genomics. They can help in understanding therapeutic targets for diseases related to cell cycle dysregulation, thereby driving the progress of tailored therapeutic interventions.

Compared to traditional gene knockout methods, our SWI5 Gene Knockout Cell Lines offer superior efficiency, specificity, and reproducibility, significantly reducing the time and resources typically required for generating knockout models. They represent a cost-effective solution with unparalleled precision for researchers aiming for reliable results.

For researchers and clinicians alike, these cell lines provide an invaluable resource, allowing for unprecedented insight into the role of the SWI5 gene in health and disease. Our company's commitment to advancing biological research through cutting-edge technology positions us as a leader in cell line development, ensuring that our offered products meet the highest standards of quality and effectiveness.

Please note that all services are for research use only. Not intended for any clinical use.

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