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SUSD4 Knockout Cell Lines

Gene: SUSD4

Official Full Name: sushi domain containing 4provided by HGNC

Gene Summary: Involved in negative regulation of complement activation, alternative pathway and negative regulation of complement activation, classical pathway. Predicted to be located in extracellular region and membrane. Predicted to be active in parallel fiber to Purkinje cell synapse and postsynaptic membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13629 SUSD4 Knockout cell line (HCT 116) Human SUSD4 1:2~1:4 Negative Online Inquiry
KO13630 SUSD4 Knockout cell line (HEK293) Human SUSD4 1:3~1:6 Negative Online Inquiry

Background

SUSD4 Gene Knockout Cell Lines are genetically modified cell lines that have undergone targeted gene editing to inactivate the SUSD4 gene, a gene implicated in various biological processes, including cell signaling and immune response regulation. By employing advanced CRISPR-Cas9 technology, these knockout cell lines enable researchers to investigate the functional role of SUSD4 in cellular contexts, providing insights into its contribution to disease mechanisms, developmental biology, or cellular metabolism.

The primary function of SUSD4 knockout cell lines lies in their ability to elucidate gene function and interaction pathways. By removing the specific genomic sequence of SUSD4, researchers can observe the resultant phenotypic changes, such as alterations in cell proliferation, differentiation, or immune interactions. This approach allows for a comprehensive understanding of SUSD4's role in a variety of physiological and pathological scenarios, making it a vital tool in experimental design.

Scientifically, the SUSD4 Gene Knockout Cell Lines hold significant importance in both research and clinical applications. They serve as invaluable models for studying diseases such as cancer and autoimmune disorders where the SUSD4 gene may play a pivotal role. These models can be utilized in drug screening and development, allowing for the identification of novel therapeutic targets or the assessment of drug efficacy and safety.

Compared to traditional cell lines that may retain normal SUSD4 expression, the knockout variants offer a clear advantage by presenting uncontaminated data about the gene's absence. This specificity reduces background noise in experimental results and enhances the reliability of conclusions drawn from research findings.

Valued by researchers and clinicians alike, SUSD4 Gene Knockout Cell Lines can foster significant advancements in the understanding and treatment of complex diseases. They streamline experimental workflows, enabling quicker hypothesis testing and increased reproducibility of results.

As a company renowned for its commitment to innovation and scientific excellence, we take pride in delivering high-quality genetic tools like the SUSD4 Gene Knockout Cell Lines. Our extensive expertise in molecular biology and rigorous validation processes ensure that our products meet the highest standards, empowering your research endeavors with confidence and precision.

Please note that all services are for research use only. Not intended for any clinical use.

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