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SUSD2 Knockout Cell Lines

Gene: SUSD2

Official Full Name: sushi domain containing 2provided by HGNC

Gene Summary: Involved in negative regulation of cell cycle G1/S phase transition and negative regulation of cell division. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13631 SUSD2 Knockout cell line (HeLa) Human SUSD2 1:3~1:6 Negative Online Inquiry
KO13632 SUSD2 Knockout cell line (HCT 116) Human SUSD2 1:2~1:4 Negative Online Inquiry
KO13633 SUSD2 Knockout cell line (A549) Human SUSD2 1:3~1:4 Negative Online Inquiry

Background

SUSD2 Gene Knockout Cell Lines are genetically modified cell lines designed to facilitate the study of the SUSD2 gene, which plays a critical role in various biological processes, including cellular adhesion and signaling. By employing advanced CRISPR/Cas9 gene-editing technology, these cell lines exhibit a complete knockout of the SUSD2 gene, enabling researchers to investigate its function and regulatory mechanisms in cellular contexts.

The primary function of the SUSD2 Gene Knockout Cell Lines is to provide an experimental platform for examining the cellular and molecular implications of deactivating SUSD2. The disruption of this gene can lead to insights into its roles in oncogenesis, stem cell biology, and immune response, allowing for a deeper understanding of tissue homeostasis and disease progression. Researchers can utilize these models to monitor changes in gene expression, alter signaling pathways, and assess cellular behavioral changes that may arise from SUSD2's absence.

The scientific importance of these knockout cell lines extends to both basic research and clinical applications. In cancer research, altered SUSD2 function may correlate with tumor progression and metastasis, presenting opportunities for novel therapeutic approaches. Furthermore, understanding the role of SUSD2 in immune cell dynamics can inform strategies in immunotherapy, where targeting specific pathways can enhance treatment efficacy.

Compared to traditional models, SUSD2 Gene Knockout Cell Lines offer a targeted approach to gene function analysis without the confounding factors often seen in whole organisms. Their generation via CRISPR technology ensures precise modifications, resulting in more reliable data.

For researchers and clinicians alike, using these cell lines provides a unique advantage: the ability to pinpoint the consequences of SUSD2 loss in a controlled environment, ultimately driving forward our knowledge and potential interventions for diseases where this gene is implicated.

Our company specializes in innovative genetic tools and cell line development, ensuring that researchers have access to high-quality, reliable biological products tailored to meet the evolving demands of contemporary science. With a commitment to excellence and innovation, we strive to support your research endeavors with our expertly engineered solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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