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SURF2 Knockout Cell Lines

Gene: SURF2

Official Full Name: surfeit 2provided by HGNC

Gene Summary: This gene shares a bidirectional promoter with surfeit 1 (SURF1; GeneID: 6834), which is located on the opposite strand. It encodes a conserved protein that is expressed in a variety of tissues. [provided by RefSeq, Jul 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35163 SURF2 Knockout cell line (HeLa) Human SURF2 1:3~1:6 Negative Online Inquiry
KO35164 SURF2 Knockout cell line (HCT 116) Human SURF2 1:2~1:4 Negative Online Inquiry
KO35165 SURF2 Knockout cell line (HEK293) Human SURF2 1:3~1:6 Negative Online Inquiry
KO35166 SURF2 Knockout cell line (A549) Human SURF2 1:3~1:4 Negative Online Inquiry

Background

SURF2 Gene Knockout Cell Lines are advanced genetically engineered models designed to facilitate exploration and understanding of the SURF2 gene's roles in cellular functioning and disease. These cell lines have been created using precise CRISPR/Cas9 gene-editing technology, enabling researchers to create stable cell lines that lack functional SURF2. This gene is crucial in mitochondrial homeostasis and the regulation of oxidative stress, which are essential processes in numerous biological systems and pathologies, including neurodegenerative diseases and cancers.

The key functionality of SURF2 Gene Knockout Cell Lines lies in their ability to mimic the pathophysiological states associated with SURF2 deficiencies, thus providing a powerful platform for studying mitochondrial dynamics and their implications on cell metabolism and survival. By comparing these knockout lines with their wild-type counterparts, researchers can elucidate the gene's regulatory mechanisms, signaling pathways, and the resultant phenotypic alterations. This makes the SURF2 knockout model particularly invaluable in investigations focused on mitochondrial dysfunction, oxidative stress responses, and potential therapeutic interventions.

The scientific importance of these cell lines extends into both academic and clinical research settings, where they can be employed for drug screening, biomarker discovery, and the development of gene therapies targeting mitochondrial diseases. Compared to traditional models, the specific advantage of SURF2 Gene Knockout Cell Lines lies in their enhanced specificity and sensitivity in studying gene function, allowing for more accurate and reproducible results.

For researchers and clinicians, the value of SURF2 Gene Knockout Cell Lines is multifaceted; they enable the exploration of novel treatment strategies, contribute to a deeper understanding of mitochondrial pathologies, and allow for high-throughput applications in pharmacological studies. Utilizing these cell lines ensures that users are equipped with cutting-edge tools that can lead to impactful scientific discoveries.

Our company has a robust history of innovation in genetic engineering and a commitment to quality, ensuring that your research is supported with reliable and validated cellular models. Choose SURF2 Gene Knockout Cell Lines to elevate your research and clinical applications in mitochondrial biology.

Please note that all services are for research use only. Not intended for any clinical use.

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