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SUCNR1 Knockout Cell Lines

Gene: SUCNR1

Official Full Name: succinate receptor 1provided by HGNC

Gene Summary: This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00249 SUCNR1 Knockout cell line (HCT 116) Human SUCNR1 1:2~1:4 Negative Online Inquiry

Background

SUCNR1 Gene Knockout Cell Lines are advanced experimental tools designed to facilitate the study of the succinate receptor (SUCNR1) in various biological contexts. This product is generated through genome editing techniques, such as CRISPR/Cas9, to create precise deletions of the SUCNR1 gene. This knockout mechanism effectively silences the gene, allowing researchers to investigate its biological functions, signaling pathways, and roles in physiology or disease without the interference of the receptor's activity.

The primary function of the SUCNR1 gene knockout cell lines is to enable the dissection of the receptor’s involvement in metabolic processes, inflammatory responses, and tumor biology. By generating these knockout models, scientists can examine the downstream effects of SUCNR1 signaling, particularly in relation to metabolic disorders and cancer, providing invaluable insight into the receptor's potential as a therapeutic target. The mechanistic understanding gained from these cell lines can significantly advance both basic and translational research.

The scientific significance of SUCNR1 knockout cell lines extends to various applications, including drug discovery, functional genomics, and personalized medicine. These cell lines serve as a platform for assessing the efficacy of new pharmacological agents targeting the SUCNR1 receptor and can be utilized in screening assays to identify novel compounds that modulate its activity. Compared to traditional methods, such as pharmacological inhibition or overexpression systems, gene knockout cell lines provide a more precise and reliable means to study receptor biology.

What sets SUCNR1 Gene Knockout Cell Lines apart from alternatives is their user-friendly nature, consistent reproductive performance, and suitability for high-throughput screening applications. These cell lines are crafted to ensure reproducibility and ease of handling, which enhances experimental efficiency while delivering robust and interpretable data.

For researchers and clinicians focused on understanding metabolic regulation and receptor signaling, SUCNR1 Gene Knockout Cell Lines offer unmatched value. They not only bolster research efforts to delineate the role of SUCNR1 in health and disease but also empower scientists to explore novel therapeutic avenues.

Our company brings extensive expertise in developing high-quality biological products tailored to the needs of the research community. With a commitment to innovation and scientific advancement, we stand ready to support your research endeavors with our specialized offerings, ensuring that you have the tools required to fulfill your investigative goals.

Please note that all services are for research use only. Not intended for any clinical use.

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