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STX6 Knockout Cell Lines

Gene: STX6

Official Full Name: syntaxin 6provided by HGNC

Gene Summary: Enables syntaxin binding activity. Involved in regulation of protein localization; retrograde transport, endosome to Golgi; and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome; perinuclear region of cytoplasm; and trans-Golgi network. Part of SNARE complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32111 STX6 Knockout cell line (HeLa) Human STX6 1:3~1:6 Negative Online Inquiry
KO32112 STX6 Knockout cell line (HCT 116) Human STX6 1:2~1:4 Negative Online Inquiry
KO32113 STX6 Knockout cell line (HEK293) Human STX6 1:3~1:6 Negative Online Inquiry
KO32114 STX6 Knockout cell line (A549) Human STX6 1:3~1:4 Negative Online Inquiry

Background

STX6 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to silence the syntaxin 6 (STX6) gene, which plays a critical role in vesicular transport processes within cells. This product provides researchers with a powerful tool for studying the functions and interactions of STX6 in various cellular contexts, particularly in relation to intracellular trafficking, membrane fusion, and protein sorting mechanisms. By eliminating the STX6 gene, researchers can observe the physiological and biochemical phenotypes that result from this gene's absence, thereby gaining insights into its role in health and disease.

The STX6 Gene Knockout Cell Lines function through CRISPR/Cas9 technology, which allows for precise and efficient gene editing. This method ensures a complete knockout of STX6, enabling researchers to analyze downstream effects on critical cellular processes, including exocytosis and endocytosis, that are essential for neurotransmitter release and hormone secretion. Such meticulous manipulation of cellular genetics provides a unique opportunity to dissect the molecular underpinnings of various diseases, including neurodegenerative disorders and metabolic syndromes.

The scientific importance of STX6 Gene Knockout Cell Lines lies in their application for various research domains, including neurobiology, cell biology, and therapeutic development. These cell lines can serve as invaluable models for testing the efficacy of drugs targeting transport pathways, advancing our understanding of cellular dysfunctions linked to STX6-related diseases. Compared to alternative models, such as wild-type or overexpression systems, the knockout approach offers specificity and reduces confounding variables, leading to more robust experimental outcomes.

Researchers and clinicians will find significant value in the STX6 Gene Knockout Cell Lines due to their ability to highlight the consequence of STX6 deficiency in a controlled laboratory setting, which not only accelerates basic research but also aids in translational studies aimed at developing novel therapeutic strategies. This model facilitates deeper investigations into molecular mechanisms and may provide critical insights that can shape future innovations in clinical practice.

Our company prides itself on its expertise in advanced genetic engineering and providing high-quality biological products. We are committed to aiding the scientific community by delivering research tools that enhance experimental accuracy and promote breakthroughs in understanding complex biological phenomena.

Please note that all services are for research use only. Not intended for any clinical use.

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