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STX16 Knockout Cell Lines

Gene: STX16

Official Full Name: syntaxin 16provided by HGNC

Gene Summary: This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene. [provided by RefSeq, Mar 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02308 STX16 Knockout cell line (HeLa) Human STX16 1:3~1:6 Negative Online Inquiry
KO02309 STX16 Knockout cell line (HCT 116) Human STX16 1:2~1:4 Negative Online Inquiry
KO02310 STX16 Knockout cell line (HEK293) Human STX16 1:3~1:6 Negative Online Inquiry
KO02311 STX16 Knockout cell line (A549) Human STX16 1:3~1:4 Negative Online Inquiry

Background

STX16 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to disrupt the STX16 gene, which encodes syntaxin 16, a protein pivotal for intracellular membrane trafficking and fusion processes. These knockout cell lines enable researchers to study the role of STX16 in various physiological and pathological contexts by eliminating its expression, thereby facilitating investigations into mechanisms of exocytosis and endocytosis, as well as cellular responses to stress and signaling pathways.

The primary function of the STX16 knockout cell lines lies in their ability to elucidate the biological roles of syntaxin 16 in cellular processes such as vesicle transport, recycling, and distribution of proteins and lipids within cells. By observing the phenotypic consequences of STX16 disruption, researchers can gain insights into diseases related to secretion deficits, neurodegenerative disorders, and cancer metastasis, among others.

Scientifically, these cell lines are invaluable not only for basic research but also for potential clinical applications in drug discovery, where understanding the pathways influenced by STX16 can lead to novel therapeutic strategies. The capability to model specific genetic alterations provides a platform for high-throughput screening of compounds targeting related pathways, thus optimizing therapeutic development.

One of the unique selling points of STX16 Gene Knockout Cell Lines is their specificity and reproducibility. Unlike alternative models that may provide ambiguous results due to off-target effects, these knockout cell lines allow for clear delineation of STX16 functions. Moreover, they are fully characterized and validated, which ensures reliability in experimental outcomes and decreases variability in data interpretation.

For researchers and clinicians, the value of STX16 Gene Knockout Cell Lines is significant: they advance our understanding of cellular mechanisms and disease models while supporting the development of innovative therapies. Furthermore, our company boasts extensive expertise in genetic engineering and cell line development, ensuring that you receive high-quality products tailored to your research needs, enabling advancements in the field of cellular and molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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