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STRBP Knockout Cell Lines

Gene: STRBP

Official Full Name: spermatid perinuclear RNA binding proteinprovided by HGNC

Gene Summary: Enables RNA binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Predicted to act upstream of or within cell motility; mechanosensory behavior; and spermatid development. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13663 STRBP Knockout cell line (HeLa) Human STRBP 1:3~1:6 Negative Online Inquiry
KO13664 STRBP Knockout cell line (HCT 116) Human STRBP 1:2~1:4 Negative Online Inquiry
KO13665 STRBP Knockout cell line (HEK293) Human STRBP 1:3~1:6 Negative Online Inquiry
KO13666 STRBP Knockout cell line (A549) Human STRBP 1:3~1:4 Negative Online Inquiry

Background

STRBP Gene Knockout Cell Lines are genetically modified cell lines specifically designed to have the STRBP (Striatal-Enriched Protein Tyrosine Phosphatase) gene completely inactivated. This innovative product is engineered using CRISPR/Cas9 technology, allowing for precise editing of the genomic locus to produce knockout phenotypes. Key functions of these cell lines include facilitating the study of STRBP's role in various cellular processes, including neuronal differentiation and synaptic plasticity. By understanding the absence of STRBP, researchers can uncover essential insights into neurodevelopmental and neurodegenerative diseases.

The scientific importance of STRBP Gene Knockout Cell Lines extends to both fundamental research and potential clinical applications. For instance, STRBP has been implicated in Huntington's disease and other neurological conditions; thus, these knockout models serve as critical tools for elucidating disease mechanisms, identifying potential therapeutic targets, and validating drug responses. In vitro studies utilizing these models can significantly contribute to the understanding of gene function and regulation in the context of diseases where STRBP expression changes.

A distinct advantage of our STRBP Gene Knockout Cell Lines is their validated background, ensuring consistent performance across experiments. Unlike traditional knockout models, which may suffer from off-target effects or incomplete knockout efficiencies, our lines are thoroughly characterized, providing high specificity that enhances experimental reproducibility. These cell lines can be easily integrated into various experimental workflows, including biochemical assays and high-throughput screening processes, thus simplifying research design for scientists.

For researchers and clinicians, the ability to model diseases with unprecedented accuracy is invaluable. The STRBP Gene Knockout Cell Lines provide an essential resource for better understanding the molecular basis of neurological disorders and advancing therapeutic interventions. Our company, with its established expertise in genetic engineering and cell line development, is dedicated to providing high-quality biological products that meet the rigorous demands of the scientific community. By choosing our STRBP Gene Knockout Cell Lines, you'll be equipping your research with a powerful tool tailored to uncover new biological insights and foster innovation in health sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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