Home / STRADB Knockout Cell Lines

STRADB Knockout Cell Lines

Gene: STRADB

Official Full Name: STE20 related adaptor betaprovided by HGNC

Gene Summary: This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09127 STRADB Knockout cell line (HeLa) Human STRADB 1:3~1:6 Negative Online Inquiry
KO09128 STRADB Knockout cell line (HCT 116) Human STRADB 1:2~1:4 Negative Online Inquiry
KO09129 STRADB Knockout cell line (HEK293) Human STRADB 1:3~1:6 Negative Online Inquiry
KO09130 STRADB Knockout cell line (A549) Human STRADB 1:3~1:4 Negative Online Inquiry

Background

STRADB Gene Knockout Cell Lines are state-of-the-art biological tools specifically engineered to facilitate the study of gene function and the mechanisms of gene-related diseases. These cell lines have been developed through precise gene editing technologies, such as CRISPR-Cas9 or TALEN, enabling the targeted knockout of specific genes. This process allows researchers to observe the resultant phenotypic changes, providing insights into gene expression and regulation while elucidating the roles of particular genes in various biological pathways.

The key functionality of STRADB Gene Knockout Cell Lines lies in their ability to mimic disease states by removing the influence of specific genes. This feature significantly aids in investigating the molecular underpinnings of diseases such as cancer, neurodegenerative disorders, and genetic syndromes. The mechanistic insights gained through these cell lines can inform drug discovery processes, enhancing the identification and validation of novel therapeutic targets.

The scientific importance of STRADB Gene Knockout Cell Lines cannot be overstated; they serve not only as a valuable resource in basic research but also have pivotal applications in translational medicine. By providing a robust platform for testing hypotheses related to gene function and disease mechanisms, these cell lines accelerate the pace of innovation in both academic research and clinical applications.

What sets STRADB Gene Knockout Cell Lines apart from alternative products is their high specificity and reliability. Each cell line is meticulously validated for gene knockout efficiency, ensuring that results are reproducible and interpretable. Furthermore, our cell lines are compatible with a wide range of applications, including high-throughput screening, CRISPR phenotyping, and pathway analysis, making them versatile solutions for diverse research needs.

Researchers and clinicians alike will find immense value in STRADB Gene Knockout Cell Lines, as they are designed to empower scientific inquiry and advance our understanding of complex biological systems. Their user-friendly design and compatibility with various assay formats simplify experimental workflows, increasing productivity in the lab.

As a company rooted in cutting-edge genomic technologies, we pride ourselves on delivering high-quality biological products tailored to meet the evolving needs of the research community. Our expertise in gene editing and cellular models ensures that STRADB Gene Knockout Cell Lines are at the forefront of scientific exploration, poised to drive breakthroughs in genetic research and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.