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STK38 Knockout Cell Lines

Gene: STK38

Official Full Name: serine/threonine kinase 38provided by HGNC

Gene Summary: This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30975 STK38 Knockout cell line (HeLa) Human STK38 1:3~1:6 Negative Online Inquiry
KO30976 STK38 Knockout cell line (HCT 116) Human STK38 1:2~1:4 Negative Online Inquiry
KO30977 STK38 Knockout cell line (HEK293) Human STK38 1:3~1:6 Negative Online Inquiry
KO30978 STK38 Knockout cell line (A549) Human STK38 1:3~1:4 Negative Online Inquiry

Background

STK38 Gene Knockout Cell Lines are specialized cellular models developed to investigate the functional roles of the STK38 (serine/threonine kinase 38) gene, a crucial regulator of various cellular processes including cell growth, proliferation, and apoptosis. These genetically modified cell lines are created using advanced CRISPR-Cas9 technology, leading to precise deletions of the STK38 gene, thereby allowing researchers to explore its biological significance and the pathways it influences.

The principal function of STK38 Gene Knockout Cell Lines lies in their ability to provide a clearer understanding of STK38-related signaling networks and their implications in diseases such as cancer, neurodegeneration, and developmental disorders. By observing the resulting phenotypic changes in these cell lines, researchers can elucidate the gene's role in cellular responses to stress, survival mechanisms, and potential therapeutic targets. This makes them an invaluable tool in both basic research and drug development.

In comparison to conventional cell lines, STK38 Knockout models offer distinct advantages by providing a more accurate representation of biological processes affected by the lack of STK38 expression. This specificity allows for a more directed investigation into the functional knockdown without the confounding effects often associated with partial inhibition or overexpression strategies.

Furthermore, the scientific importance of these knockout cell lines extends into translational medicine, where they can aid in the discovery of novel biomarkers or therapeutic agents against STK38-dependent pathways. For researchers and clinicians alike, the ability to manipulate gene expression with high specificity enhances experimental rigor and can accelerate the translation of findings from bench to bedside.

Our company, renowned for its dedication to advancing genetic research and innovation, offers these STK38 Gene Knockout Cell Lines as part of our commitment to empowering the scientific community. By providing high-quality, meticulously validated cellular models, we facilitate groundbreaking research that can potentially lead to significant advancements in biomedical sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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