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STK17A Knockout Cell Lines

Gene: STK17A

Official Full Name: serine/threonine kinase 17aprovided by HGNC

Gene Summary: This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04921 STK17A Knockout cell line (HeLa) Human STK17A 1:3~1:6 Negative Online Inquiry
KO04922 STK17A Knockout cell line (HCT 116) Human STK17A 1:2~1:4 Negative Online Inquiry
KO04923 STK17A Knockout cell line (HEK293) Human STK17A 1:3~1:6 Negative Online Inquiry
KO04924 STK17A Knockout cell line (A549) Human STK17A 1:3~1:4 Negative Online Inquiry

Background

STK17A Gene Knockout Cell Lines are precisely engineered cellular models that facilitate the exploration of the STK17A gene, which encodes a protein associated with cellular stress responses and apoptosis. By employing the CRISPR-Cas9 gene-editing technology, these knockout cell lines have been constructed to specifically disrupt the STK17A locus, enabling researchers to study the downstream effects of STK17A depletion on cell biology.

The primary function of STK17A Gene Knockout Cell Lines lies in their ability to mimic the loss-of-function scenarios in a controlled laboratory setting. When STK17A is knocked out, the resultant cellular phenotype can provide insights into processes such as apoptosis induction, stress response regulation, and tumorigenesis. Researchers can utilize these cells to investigate signaling pathways, discover potential drug targets, and identify biomarkers related to various diseases, particularly cancer.

The scientific importance of these cell lines extends to both basic and applied research, particularly within oncology and pharmacology. By elucidating the role of STK17A in cellular processes, these models facilitate the development of targeted therapies and better understanding of cancer mechanisms.

Unique advantages of STK17A Gene Knockout Cell Lines include their specificity, reproducibility, and versatility. Unlike traditional knockout models, which may exhibit off-target effects, these lines provide a reliable platform for experimentation with a defined genetic modification. Additionally, their adaptability for various cell culture systems ensures that researchers can seamlessly integrate them into existing workflows.

For researchers and clinicians seeking to advance their understanding of stress response mechanisms and apoptosis-related diseases, STK17A Gene Knockout Cell Lines offer an invaluable tool. They empower investigations that can lead to groundbreaking discoveries in molecular biology and therapeutics.

With a commitment to innovation and excellence, our company specializes in producing high-quality, expertly designed biological research products, ensuring that researchers have the tools they need to achieve their scientific objectives effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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