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STIMATE Knockout Cell Lines

Gene: STIMATE

Official Full Name: STIM activating enhancerprovided by HGNC

Gene Summary: Enables calcium channel regulator activity. Involved in activation of store-operated calcium channel activity and store-operated calcium entry. Located in cortical endoplasmic reticulum; endoplasmic reticulum membrane; and endoplasmic reticulum-plasma membrane contact site. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00270 STIMATE Knockout cell line (HeLa) Human STIMATE 1:3~1:6 Negative Online Inquiry

Background

STIMATE Gene Knockout Cell Lines are a cutting-edge biological product designed to facilitate the study of gene function and regulation through the precise dissection of gene knockouts. These cell lines are developed using advanced CRISPR-Cas9 gene-editing technology, enabling the specific targeting and disruption of genes within the genomic DNA of cultured cells. The mechanisms by which STIMATE Gene Knockout Cell Lines operate involve the introduction of targeted double-strand breaks in the DNA, followed by repair processes that often result in insertions or deletions, effectively knocking out the targeted gene's expression.

The scientific importance of these cell lines cannot be overstated, especially in research and clinical settings, as they serve as pivotal tools for understanding gene roles in various biological pathways and diseases. Researchers can utilize these knockout models to elucidate gene function, identify genetic interactions, and explore novel therapeutic targets for conditions ranging from cancer to genetic disorders. In pharmaceutical development, STIMATE Gene Knockout Cell Lines can accelerate drug screening processes by providing more reliable, cell-based models for efficacy and toxicity studies.

One key advantage of STIMATE Gene Knockout Cell Lines is their high efficiency and specificity in gene editing compared to traditional methods such as siRNA or gene silencing techniques. This specificity minimizes off-target effects and enhances reproducibility, making them invaluable for researchers seeking robust experimental outcomes. Additionally, these cell lines are readily available and easy to use, saving researchers time and resources during experimental planning and execution.

The value of STIMATE Gene Knockout Cell Lines is particularly pronounced for researchers and clinicians aiming to uncover the complexities behind gene expression and its influence on biological systems. With our commitment to delivering high-quality biological products, coupled with our expertise in genetic engineering, we proudly support the scientific community in advancing discoveries that may lead to new therapies and enhanced understanding of genetic diseases.

Please note that all services are for research use only. Not intended for any clinical use.

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