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STEAP1B Knockout Cell Lines

Gene: STEAP1B

Official Full Name: STEAP family member 1Bprovided by HGNC

Gene Summary: Predicted to be located in membrane. Predicted to be active in endosome and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21067 STEAP1B Knockout cell line (HEK293) Human STEAP1B 1:3~1:6 Negative Online Inquiry

Background

STEAP1B Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to contain a targeted deletion of the STEAP1B gene, which encodes a member of the six-transmembrane epithelial antigen of prostate 1 (STEAP) family. This product provides researchers with a powerful tool to study the gene's function and its implications in various biological processes, including cancer progression and immune response.

The primary mechanism of action involves the use of CRISPR-Cas9 technology, leading to precise modifications in the genomic sequence of the STEAP1B gene. By creating these knockout cell lines, researchers can effectively analyze the absence of STEAP1B and assess its role in cellular functions such as proliferation, differentiation, and apoptosis. In particular, studying STEAP1B knockout models helps elucidate mechanisms underlying prostate cancer biology, providing insights into potential therapeutic targets and biomarkers.

The scientific importance of STEAP1B gene knockout cell lines stems from their applications in both basic and applied research settings. They serve as essential models for validating hypotheses regarding gene function, investigating cellular responses to various stimuli, and screening potential pharmacological agents. Furthermore, the understanding of STEAP1B's role can facilitate the development of novel cancer therapies and diagnostic tools.

Compared to conventional cell lines, the STEAP1B knockout versions offer unique advantages, including a clear phenotypic distinction that allows straightforward monitoring of gene-related pathways. They also eliminate the confounding effects of gene expression variability seen in wild-type cells, thereby enhancing the reproducibility and reliability of experimental results.

Researchers and clinicians will find immense value in these cell lines due to their ability to provide robust and consistent data, ultimately paving the way for advancements in therapeutic strategies and contributing to improved patient outcomes.

Our company specializes in the development of high-quality biological products tailored for cutting-edge research applications. With a deep understanding of genetic engineering techniques and a commitment to precision and reliability, we aim to empower researchers in their quest for scientific breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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