Gene: STAP2
Official Full Name: signal transducing adaptor family member 2provided by HGNC
Gene Summary: This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13706 | STAP2 Knockout cell line (HCT 116) | Human | STAP2 | 1:2~1:4 | Negative | Online Inquiry |
KO13707 | STAP2 Knockout cell line (HEK293) | Human | STAP2 | 1:3~1:6 | Negative | Online Inquiry |
STAP2 Gene Knockout Cell Lines are genetically engineered cell lines characterized by the targeted disruption of the STAP2 (Signal Transducer and Activator of Transcription 2) gene. This innovative product is developed using advanced CRISPR/Cas9 gene-editing technology, leading to a precise knockout of STAP2, which is implicated in various cellular signaling pathways, immune responses, and metabolic processes. By creating a cellular model devoid of the STAP2 gene, researchers can investigate the role of this gene in disease pathogenesis, drug responses, and cellular functions.
The primary mechanism of STAP2 Gene Knockout Cell Lines lies in the loss of function of the STAP2 protein, which affects the pathways it regulates. Without STAP2, cells exhibit altered behavior in response to external stimuli, making these knockout lines indispensable for elucidating the biological roles of STAP2 in both normal physiology and disease contexts. These cell lines serve as a critical tool in both basic research and clinical applications, providing insights into immune responses and potential therapeutic mechanisms.
One of the key advantages of STAP2 Gene Knockout Cell Lines is the reliability and reproducibility of the CRISPR-based modification, which stands in contrast to traditional gene-editing methods that may produce variable results. These knockout lines are meticulously validated to ensure the accuracy and specificity of the gene disruption. This level of confidence empowers researchers and clinicians to draw meaningful conclusions from their experiments.
The value of STAP2 Gene Knockout Cell Lines is underscored by their versatility; they are applicable across a range of disciplines, including immunology, cancer biology, and pharmacology. By utilizing these cell lines, target users can uncover novel functional insights, identify potential biomarkers, and explore therapeutic avenues, making them an essential asset in the quest for innovative treatments and advancements in medical science.
Our company is committed to supporting the scientific community with high-quality, rigorously designed biological products. With a deep understanding of genetic engineering and a portfolio of reliable tools, we aim to empower researchers and clinicians to push the boundaries of discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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