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SSBP1 Knockout Cell Lines

Gene: SSBP1

Official Full Name: single stranded DNA binding protein 1provided by HGNC

Gene Summary: SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35235 SSBP1 Knockout cell line (HeLa) Human SSBP1 1:3~1:6 Negative Online Inquiry
KO35236 SSBP1 Knockout cell line (HCT 116) Human SSBP1 1:2~1:4 Negative Online Inquiry
KO35237 SSBP1 Knockout cell line (HEK293) Human SSBP1 1:3~1:6 Negative Online Inquiry
KO35238 SSBP1 Knockout cell line (A549) Human SSBP1 1:3~1:4 Negative Online Inquiry

Background

SSBP1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of the SSBP1 (Single-stranded DNA-binding protein 1) gene's functions and its associated biological pathways. By employing CRISPR/Cas9 gene editing technology, these knockout cell lines exhibit a complete absence of SSBP1 protein, providing researchers with invaluable tools to dissect the role of this gene in crucial cellular processes such as DNA replication, repair, and mitochondrial function.

The primary function of SSBP1 involves binding to single-stranded DNA, which is critical for maintaining genomic stability and orchestrating mitochondrial DNA replication. The knockout of this gene results in a cellular context where the implications of disrupted SSBP1 functionality can be studied, shedding light on potential mechanisms behind various diseases, including cancer and mitochondrial dysfunction. This advanced model allows scientists to simulate and analyze the effects of SSBP1 deficiency, making it a pivotal resource in both basic and applied research.

Scientifically, SSBP1 Gene Knockout Cell Lines hold significant promise in elucidating the pathways that underlie genomic instability, thus paving the way for novel therapeutic strategies. The potential application of these cell lines extends to drug discovery and the testing of therapeutics aimed at restoring normal gene function or compensating for SSBP1 loss.

Compared to conventional cell lines, our SSBP1 knockout models offer unparalleled specificity and reliability, ensuring that researchers can achieve reproducible results. Additionally, the comprehensive documentation and user-friendly protocols provided with the product distinguish our offering, making it easier for scientists to implement in various research settings.

In summary, SSBP1 Gene Knockout Cell Lines are essential for cutting-edge research, bridging gaps in our understanding of DNA dynamics and its implications for human health. Our company, a leader in the development of high-quality biological products, is committed to providing researchers with reliable, innovative tools to advance scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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