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SS18 Knockout Cell Lines

Gene: SS18

Official Full Name: SS18 subunit of BAF chromatin remodeling complexprovided by HGNC

Gene Summary: Enables nuclear receptor coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Part of SWI/SNF complex. Implicated in synovial sarcoma. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01855 SS18 Knockout cell line (HeLa) Human SS18 1:3~1:6 Negative Online Inquiry
KO01856 SS18 Knockout cell line (HCT 116) Human SS18 1:2~1:4 Negative Online Inquiry
KO01857 SS18 Knockout cell line (HEK293) Human SS18 1:3~1:6 Negative Online Inquiry
KO01858 SS18 Knockout cell line (A549) Human SS18 1:3~1:4 Negative Online Inquiry

Background

SS18 Gene Knockout Cell Lines are specialized cellular models engineered to exhibit complete disruption of the SS18 gene, a critical component implicated in various oncogenic processes. This innovative product leverages the power of CRISPR-Cas9 gene-editing technology to precisely induce targeted mutations in the SS18 gene, leading to the establishment of knockout cell lines that effectively model the gene's loss of function in a controlled environment.

These cell lines serve as invaluable tools for dissecting the biological roles of the SS18 gene in cellular pathways, particularly in the context of cancer research. By observing the phenotypic and functional changes in SS18-deficient cells, researchers can elucidate the mechanisms underlying tumorigenesis and identify potential therapeutic targets. Furthermore, the SS18 Gene Knockout Cell Lines can support high-throughput screening assays, enabling the discovery of novel compounds or genetic interactions that may regain control over aberrant signaling pathways.

What sets these cell lines apart is their superior reliability and authenticity in replicating the physiological conditions of human tissues. In contrast to traditional knockdown strategies, which only partially reduce gene expression, the knockout approach provides complete functional ablation, offering clear insights into gene function and regulation. Additionally, these cell lines are rigorously validated for consistent performance across various assays, ensuring reproducibility and accuracy in research outcomes.

For researchers and clinicians alike, the SS18 Gene Knockout Cell Lines represent a significant advancement in experimental biology. Their application extends beyond understanding SS18’s role in cancer, providing foundational models for exploring broader implications in developmental biology and genetic disorders. With a focus on innovation and excellence, our company brings extensive expertise in cellular model development, assuring customers that they are equipped with reliable, high-quality products to support their pioneering research.

Please note that all services are for research use only. Not intended for any clinical use.

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