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SRRM4 Knockout Cell Lines

Gene: SRRM4

Official Full Name: serine/arginine repetitive matrix 4provided by HGNC

Gene Summary: SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24814 SRRM4 Knockout cell line (HeLa) Human SRRM4 1:3~1:6 Negative Online Inquiry

Background

SRRM4 Gene Knockout Cell Lines are specifically engineered cellular systems designed to study the functional role of the SRRM4 gene, a critical component implicated in RNA splicing and cellular differentiation. By utilizing CRISPR-Cas9 technology, these cell lines offer precise deletion of the SRRM4 gene, allowing researchers to delve into its mechanisms and contributions to various biological processes.

The primary function of these knockout cell lines is to facilitate the exploration of SRRM4's role in the regulation of gene expression and its influence on splicing variations that can lead to myriad diseases, including certain cancers and neurodevelopmental disorders. Through the absence of the SRRM4 gene, researchers can observe phenotypic changes, analyze alternative splicing patterns, and study cellular responses to various stimuli, providing invaluable insights into molecular pathways and potential therapeutic targets.

The scientific importance of SRRM4 Gene Knockout Cell Lines extends to both basic research and clinical applications. In research, these models are vital for elucidating the underlying mechanisms of diseases linked to aberrant splicing. Clinically, understanding the functions of SRRM4 can lead to novel diagnostic biomarkers and therapeutic strategies, particularly in oncology and neurology.

Compared to traditional models, SRRM4 Gene Knockout Cell Lines offer superior specificity and reproducibility in research findings. The ability to generate precise knockouts using cutting-edge gene-editing technology minimizes off-target effects, leading to more reliable data. Additionally, these cell lines are readily adaptable for high-throughput screening applications, streamlining the study of SRRM4 interactions in drug discovery processes.

For researchers and clinicians aiming to unravel the complex roles of RNA splicing in health and disease, SRRM4 Gene Knockout Cell Lines represent a groundbreaking tool that provides the necessary functionality and flexibility. Our company, with its commitment to innovation and quality in biological research products, ensures that you receive top-tier cell lines that empower your scientific endeavors and accelerate discoveries in cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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