Gene: SRRM2
Official Full Name: serine/arginine repetitive matrix 2provided by HGNC
Gene Summary: Enables C2H2 zinc finger domain binding activity. Involved in mRNA splicing, via spliceosome. Located in Cajal body and nuclear speck. Part of U2-type catalytic step 2 spliceosome and U2-type precatalytic spliceosome. Implicated in autosomal dominant intellectual developmental disorder. Biomarker of Parkinson's disease. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04890 | SRRM2 Knockout cell line (HeLa) | Human | SRRM2 | 1:3~1:6 | Negative | Online Inquiry |
KO04891 | SRRM2 Knockout cell line (HCT 116) | Human | SRRM2 | 1:2~1:4 | Negative | Online Inquiry |
KO04892 | SRRM2 Knockout cell line (HEK293) | Human | SRRM2 | 1:3~1:6 | Negative | Online Inquiry |
KO04893 | SRRM2 Knockout cell line (A549) | Human | SRRM2 | 1:3~1:4 | Negative | Online Inquiry |
SRRM2 Gene Knockout Cell Lines are specially engineered human cell lines in which the SRRM2 gene, known to play a critical role in pre-mRNA splicing and gene regulation, has been effectively disrupted or "knocked out." This knockout allows researchers to study the downstream effects of SRRM2 absence, particularly its implications in splicing errors and various biological processes such as cell proliferation, differentiation, and gene expression. By utilizing CRISPR-Cas9 gene-editing technology, our cell lines ensure precision and specificity in the disruption of the SRRM2 gene, facilitating investigations into its functional contributions in cellular contexts.
The primary function of these knockout cell lines is to serve as a valuable tool for understanding the molecular pathways and mechanisms related to mRNA processing. Researchers can leverage these models to explore how the loss of SRRM2 affects cellular health and function, and may further gain insights into its potential link to diseases such as cancer, where splicing regulation is frequently compromised.
In clinical and research settings, understanding the role of SRRM2 has significant implications for advancing targeted therapies and improving our grasp of gene expression dysregulation. The SRRM2 Gene Knockout Cell Lines provide a unique opportunity to investigate the cellular mechanisms underlying various disorders, thereby paving the way for novel therapeutic strategies.
These knockout cell lines offer distinct advantages over traditional cell lines, as they provide a more authentic model of gene function reflecting true physiological relevance. Furthermore, the precision of the CRISPR approach minimizes off-target effects, enhancing data reliability.
For researchers and clinicians focused on genetics, cell biology, or molecular mechanisms of disease, this product is an indispensable tool that promises to enhance your studies and contribute to significant advancements in the field. As a leading provider of high-quality biological products, our company prides itself on delivering innovative and reliable solutions, with an experienced team dedicated to supporting your research goals effectively. Choose SRRM2 Gene Knockout Cell Lines to bolster your investigations and contribute to meaningful scientific discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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