Home / SRPX Knockout Cell Lines

SRPX Knockout Cell Lines

Gene: SRPX

Official Full Name: sushi repeat containing protein X-linkedprovided by HGNC

Gene Summary: Predicted to be an extracellular matrix structural constituent. Predicted to be involved in phagolysosome assembly. Predicted to act upstream of or within several processes, including negative regulation of cell proliferation involved in contact inhibition; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; and response to endoplasmic reticulum stress. Located in collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34203 SRPX Knockout cell line (HeLa) Human SRPX 1:3~1:6 Negative Online Inquiry
KO34204 SRPX Knockout cell line (HCT 116) Human SRPX 1:2~1:4 Negative Online Inquiry
KO34205 SRPX Knockout cell line (HEK293) Human SRPX 1:3~1:6 Negative Online Inquiry
KO34206 SRPX Knockout cell line (A549) Human SRPX 1:3~1:4 Negative Online Inquiry

Background

SRPX Gene Knockout Cell Lines are specifically engineered cellular models in which the SRPX gene has been selectively disrupted. These knockout systems serve as powerful tools for elucidating the biological functions of the SRPX gene, known for its involvement in neuronal development and synaptic function. By providing a cellular context where the SRPX gene expression is completely ablated, researchers can gain deeper insights into the molecular pathways and phenotypic consequences associated with its loss.

The main function of SRPX Gene Knockout Cell Lines is to facilitate the study of gene function and related signaling cascades in a controlled environment. The mechanism through which these cell lines operate relies on advanced gene editing technologies, such as CRISPR-Cas9, which enable precise modifications to the genome. By studying these knockout cell lines, scientists can assess the impact of SRPX deficiency on cellular processes like differentiation, apoptosis, and signaling, contributing to a broader understanding of neurogenetic disorders.

The scientific importance of SRPX Gene Knockout Cell Lines is underscored by their relevance in both research and clinical settings. They are invaluable for exploring the pathogenesis of conditions such as schizophrenia, where SRPX has been implicated. Furthermore, these cell lines enable the development of targeted therapies informed by mechanistic insights into SRPX-related pathways.

Compared to traditional methods, SRPX Gene Knockout Cell Lines offer several advantages. Unlike transient transfection methods, these knockout models provide stable, long-term expression patterns and reveal cellular responses to SRPX disruption over time. This stability enables more reproducible results and productive longitudinal studies, enhancing the quality of research outcomes.

Researchers and clinicians would find this product particularly valuable for accelerating the identification of therapeutic targets and validating drug screening processes. The ability to investigate the fundamental aspects of synaptic biology and neurodevelopmental disorders using these specialized cell lines cannot be overstated; it broadens the scope of experimental approaches internationally.

At our company, we pride ourselves on our expertise in developing and providing high-quality biological products that empower researchers and clinicians alike. Our commitment to scientific excellence and innovation ensures that the SRPX Gene Knockout Cell Lines will serve as a crucial resource in advancing understanding and treatment of complex genetic disorders.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.