Gene: SRMS
Official Full Name: src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sitesprovided by HGNC
Gene Summary: Enables protein tyrosine kinase activity. Involved in peptidyl-tyrosine autophosphorylation and positive regulation of TORC1 signaling. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35214 | SRMS Knockout cell line (HCT 116) | Human | SRMS | 1:2~1:4 | Negative | Online Inquiry |
SRMS Gene Knockout Cell Lines are expertly engineered cellular models designed to facilitate the investigation of SRMS (Src-Related Kinase in Megakaryocytes) gene function and regulation. These cell lines are generated through advanced CRISPR/Cas9 gene editing technology, ensuring precise knockout of the SRMS gene, which encodes a member of the Src family of tyrosine kinases known to play pivotal roles in cell growth, differentiation, and motility.
The primary function of SRMS Gene Knockout Cell Lines lies in their ability to enable researchers to dissect the biological pathways mediated by the SRMS gene. By providing a platform for loss-of-function studies, these knockout cell lines allow for an in-depth understanding of the molecular mechanisms underpinning various cellular processes such as signal transduction, cytoskeletal dynamics, and cellular interactions within the hematopoietic system. Such knowledge is critical for elucidating the gene's involvement in diseases, including hematologic malignancies, cardiovascular diseases, and other pathological conditions.
In the context of scientific research and clinical applications, the SRMS Gene Knockout Cell Lines serve as a valuable resource for drug discovery, biomarker identification, and therapeutic development. They offer researchers the capability to model disease states and assess potential interventions with high specificity and biological relevance. Compared to traditional methods such as RNA interference, these cell lines provide a more stable and permanent genetic alteration, enhancing reproducibility and facilitating longitudinal studies.
What sets our SRMS Gene Knockout Cell Lines apart is the stringent quality control and validation processes implemented during their development. Each cell line is thoroughly characterized to confirm the successful knockout of the SRMS gene, ensuring reliable experimental outcomes. Additionally, we offer comprehensive technical support and resources to assist users in maximizing the utility of these cell lines in their research endeavors.
In conclusion, the SRMS Gene Knockout Cell Lines represent a cutting-edge advancement in gene study tools, empowering researchers and clinicians alike to unravel the complexities of cellular signaling and disease pathology. With our company's commitment to excellence and innovation in biotechnology, we ensure that our products meet the highest standards of quality and scientific rigor, positioning them as indispensable tools in the biological research landscape.
Please note that all services are for research use only. Not intended for any clinical use.
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