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SRI Knockout Cell Lines

Gene: SRI

Official Full Name: sorcinprovided by HGNC

Gene Summary: This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene. [provided by RefSeq, Mar 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35253 SRI Knockout cell line (HeLa) Human SRI 1:3~1:6 Negative Online Inquiry
KO35254 SRI Knockout cell line (HCT 116) Human SRI 1:2~1:4 Negative Online Inquiry
KO35255 SRI Knockout cell line (HEK293) Human SRI 1:3~1:6 Negative Online Inquiry
KO35256 SRI Knockout cell line (A549) Human SRI 1:3~1:4 Negative Online Inquiry

Background

SRI Gene Knockout Cell Lines are genetically engineered cell lines in which specific genes have been disrupted or knocked out to study the resultant phenotypic effects and biological pathways. This sophisticated technology utilizes CRISPR-Cas9 gene-editing techniques, enabling precise alterations in genomic sequences. The key function of these cell lines is their ability to facilitate the investigation of gene function, identify novel drug targets, and explore disease mechanisms in various biological contexts.

By selectively inactivating genes, researchers can effectively elucidate the roles of individual genes in cellular processes, signal transduction, and metabolic pathways. These knockout models are invaluable in pharmacology, toxicology, and cancer research, providing a robust platform for the development of therapeutics and the understanding of gene-environment interactions. Their application extends to studying complex diseases such as neurodegenerative disorders, cardiovascular diseases, and other conditions where gene dysfunction plays a critical role.

SRI Gene Knockout Cell Lines stand out from alternative products due to their comprehensive validation and characterization, ensuring high reproducibility and reliability in experimental outcomes. They are developed using well-established human and animal cell lines, providing a familiar framework for researchers to translate findings into meaningful biological insights. Furthermore, our team of experts dedicates itself to continuous improvements in gene-editing technology, distinguishing our offering with a commitment to cutting-edge science and customer support.

For researchers and clinicians, SRI Gene Knockout Cell Lines are not just a product; they are a gateway to discovering therapeutic interventions and understanding fundamental biological mechanisms. Our dedication to quality assurance and scientific rigor ensures that customers receive products that propel their research forward, highlighting our position as leaders in the field of biological products and gene-editing technology.

Please note that all services are for research use only. Not intended for any clinical use.

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