Gene: SRGN
Official Full Name: serglycinprovided by HGNC
Gene Summary: This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35944 | SRGN Knockout cell line (HeLa) | Human | SRGN | 1:3~1:6 | Negative | Online Inquiry |
KO35945 | SRGN Knockout cell line (A549) | Human | SRGN | 1:3~1:4 | Negative | Online Inquiry |
SRGN Gene Knockout Cell Lines are genetically engineered cell lines designed to specifically delete the SRGN gene, which encodes the protein secretagogin involved in neurocognitive functions and cellular signaling. The knockout of this gene serves as a vital tool for researchers exploring the molecular mechanisms underlying various neurological conditions, including Alzheimer's disease and schizophrenia. These tailored cell lines allow for precise investigation into the functional roles of SRGN in cell development, differentiation, and signaling pathways.
The key function of SRGN Gene Knockout Cell Lines is their ability to provide a controlled environment for observing the downstream effects of SRGN deficiency. Researchers can utilize techniques such as CRISPR/Cas9 gene editing to create these knockout models, fostering the understanding of gene function and the ramifications of gene loss on cellular behavior. By elucidating the pathways influenced by SRGN, scientists can identify potential therapeutic targets, paving the way for innovative treatments.
The scientific importance of these cell lines is substantial, as they enable translational research in understanding complex neurological disorders. Their applications span a range of settings, from academic research investigating fundamental biological questions to clinical research focusing on developing new pharmaceuticals or therapeutic strategies.
What sets SRGN Gene Knockout Cell Lines apart from alternatives is their specificity and reliability. Unlike generic cell lines, these models are validated for SRGN knockout efficacy and offer consistent performance in experiments, reducing variability and enhancing reproducibility crucial for scientific inquiry. Furthermore, alongside our bioinformatics support and comprehensive user manual, we facilitate researchers in maximizing the potential of these cell lines in their investigations.
In conclusion, SRGN Gene Knockout Cell Lines offer a powerful resource for researchers and clinicians aiming to deepen their understanding of SRGN-related pathologies. Our company, with a strong commitment to advancing genetic research and developing innovative biological tools, provides the expertise and reliable products necessary to empower your studies and facilitate breakthroughs in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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