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SPX Knockout Cell Lines

Gene: SPX

Official Full Name: spexin hormoneprovided by HGNC

Gene Summary: The protein encoded by this gene is a hormone involved in modulation of cardiovascular and renal function. It has also been shown in rats to cause weight loss. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25923 SPX Knockout cell line (A549) Human SPX 1:3~1:4 Negative Online Inquiry

Background

SPX Gene Knockout Cell Lines are expertly engineered cellular models specifically designed to facilitate the study of gene function through targeted gene disruption. Utilizing advanced CRISPR-Cas9 technology, these cell lines have been developed to precisely knock out specific genes of interest, allowing researchers to dissect molecular pathways and understand the role of individual genes in cellular processes.

The key mechanism of action behind SPX Gene Knockout Cell Lines lies in their precise genome editing capabilities. CRISPR-Cas9 generates double-strand breaks at predetermined genomic locations, leading to non-homologous end joining (NHEJ) that results in the introduction of small insertion/deletion mutations. This targeted approach eliminates gene expression, enabling the study of gene knockout phenotypes without the confounding effects seen in broader genetic manipulation techniques.

Scientifically, SPX Gene Knockout Cell Lines play a critical role in various research applications, including functional genomics, drug discovery, and disease modeling. They empower researchers to explore gene-disease relationships, identify potential therapeutic targets, and investigate the mechanistic effects of gene disruption on cell behavior. In clinical settings, these cell lines can contribute significantly to personalized medicine strategies by providing models that more accurately reflect patient-specific genetic contexts.

Compared to traditional knockout models that may involve lengthy processes of animal breeding and ethical considerations, SPX Gene Knockout Cell Lines offer rapid, scalable, and cost-effective solutions. They reduce time-to-result in experimental workflows, allowing for efficient screening of gene functions and drug efficacy. Additionally, each cell line comes with detailed validation data, ensuring reliability and reproducibility in results.

The value of SPX Gene Knockout Cell Lines to researchers and clinicians lies in their ability to enhance the understanding of complex biological systems and accelerate the translation of findings into practical applications. By leveraging our extensive expertise in genetic engineering and cellular biology, our company is committed to providing robust and innovative products such as SPX Gene Knockout Cell Lines that drive scientific discovery and enable advancements in therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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